Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review
ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh +14 more
wiley +1 more source
Gender-specific function of melatonin receptor (MTRI) in gonads of red swamp crayfish, Procambarus clarkii. [PDF]
Hu M +7 more
europepmc +1 more source
An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston +2 more
wiley +1 more source
Regulation of therapeutic protein release in response to circadian biomarkers. [PDF]
Franko N +6 more
europepmc +1 more source
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang +5 more
wiley +1 more source
Melatonin mitigates dichlorvos-induced derangements in the testes and epididymis of male Wistar rats. [PDF]
Ajani OS, Samuel ES.
europepmc +1 more source
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities
Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou +5 more
wiley +1 more source
Molecular pathways affecting reproductive efficiency in seasonal breeders: prospects and implications for improving fertility in donkeys. [PDF]
Akhtar MF, Ali S, Hassan F, Changfa W.
europepmc +1 more source
MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman +7 more
wiley +1 more source

