Results 291 to 300 of about 2,728,981 (353)

Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia‐reperfusion injury by improving mitochondrial quality control: Role of SIRT6

Journal of Pineal Research, 2020
Targeting mitochondrial quality control with melatonin has been found promising for attenuating diabetic cardiomyopathy (DCM), although the underlying mechanisms remain largely undefined.
Liming Yu, Xue Dong, Xiaodong Xue, Shu-hua Xu, Xu Zhang, Yinli Xu, Zhishang Wang, Yang Wang, Hao Gao, Yangzhi Liang, Yang Yang, Huishan Wang   +11 more
semanticscholar   +1 more source

Melatonin and Melatonin Receptors in Neuroprotection

2016
Melatonin (Mel) is a neurohormone which is synthesized from tryptophan with the activation of beta-adrenergic receptors of the pineal gland [2, 11, 36]. It is chemically known as N-acetyl-5-methoxytryptamine [1]. The main task of this hormone is adjusting the rhythm of the body and protecting the biological clock of the body.
Omur Gulsum Deniz, Aysın Pınar Turkmen, Mehmet Emin Onger, Berrin Zuhal Altunkaynak, Suleyman Kaplan   +4 more
openaire   +1 more source

Docking studies for melatonin receptors

Expert Opinion on Drug Discovery, 2017
Melatonin is a neurohormone that controls many relevant physiological processes beyond the control of circadian rhythms. Melatonin's actions are carried out by two main types of melatonin receptors; MT1 and MT2. These receptors are important, and not just because of the biological actions of its natural agonist; but also, because melatonin analogues ...
Awad Alkozia, Hanan, Sánchez Montero, José, Doadrio Villarejo, Antonio Luis, Pintor Just, Jesús Jerónimo   +3 more
openaire   +3 more sources

Melatonin Receptors

Annual Review of Pharmacology and Toxicology, 1991
D N, Krause, M L, Dubocovich
openaire   +3 more sources

Melatonin receptor structures shed new light on melatonin research

Journal of Pineal Research, 2019
AbstractThe tryptophan derivative melatonin is an evolutionary old molecule that is involved in a pleiotropy of physiological functions. In humans, age‐related decline of circulating melatonin levels and/or dysregulation of its circadian synthesis pattern have been associated with several disorders and disease states.
Erika Cecon, Lei Liu, Ralf Jockers
openaire   +2 more sources

Melatonin Receptors and Melatonin Inhibition of Duck Salt Gland Secretion

General and Comparative Endocrinology, 1999
Most of the NaCl ingested by marine birds is reabsorbed from renal filtrate and excreted by the cephalic salt glands as a hypertonic NaCl secretion (SGS). Ducks have salt glands and their kidney cells have melatonin receptors. Melatonin affects glomerular filtration rate and tubular uptake of sodium (Na(+)) in mammals.
Poon, AMS, Ching, ACT, Hughes, MR, Pang, SF   +3 more
openaire   +4 more sources

Melatonin receptor in birds

2010
Abstract no.
Brown, GM, Pang, SF, Poon, AMS, Pang, CS
openaire   +2 more sources

Melatonin receptors, melatonin metabolizing enzymes and cyclin D1 in human breast cancer

Journal of Receptor and Signal Transduction Research, 2011
O. Rögelsperger, Katrin Wlcek, C. Ekmekcioglu, S. Humpeler, M. Svoboda, R. Königsberg, M. Klimpfinger, W. Jäger, T. Thalhammer   +8 more
semanticscholar   +1 more source

Nuclear melatonin receptors

Zhurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia»
Мелатонин – гормон, продуцируемый в центральной нервной системе (эпифизе) и периферических тканях (аппендиксе, поджелудочной железе, надпочечниках, тимусе, простате, яичниках, плаценте). Его секретируют клетки крови (тромбоциты, лимфоциты и эозинофилы) и эндотелий.
openaire   +1 more source

Serotonin 1A receptors, melatonin, and the proportional control thermostat in patients with winter depression.

Archives of General Psychiatry, 1998
P. Schwartz, N. Rosenthal, T. Wehr
semanticscholar   +1 more source