Results 221 to 230 of about 2,325,434 (292)

Finerenone and semaglutide: Role in heart failure with reduced ejection fraction. [PDF]

World J Cardiol
Gulzar MAR.
europepmc   +1 more source

From Receptor to Repair: The Mechanistic Basis of Mineralocorticoid Receptor Antagonism in Acute Kidney Injury and CKD. [PDF]

Kidney360
Liu R, Lu Y, Juncos LA.
europepmc   +1 more source

Aldosterone and Diabetes Risk: An Association in Need of Mechanistic Insights.

J Clin Endocrinol Metab
Echouffo-Tcheugui JB, Dagogo-Jack S.
europepmc   +1 more source

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Roles of Mineralocorticoid Receptors in Cardiovascular and Cardiorenal Diseases.

Annual Review of Physiology, 2022
Mineralocorticoid receptor (MR) activation in the heart and vessels leads to pathological effects, such as excessive extracellular matrix accumulation, oxidative stress, and sustained inflammation.
J. Barrera-Chimal, Benjamin Bonnard, F. Jaisser   +2 more
semanticscholar   +1 more source

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

Proceedings of the National Academy of Sciences of the United States of America, 2005
Henk Karst, Günther Schütz
exaly   +2 more sources

Mineralocorticoid Receptor Blockers: Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonists

Current Hypertension Reports, 2020
Recently, nonsteroidal mineralocorticoid receptor (MR) antagonists (MRAs), which have been proposed to be called MR blockers (MRBs), have become available for clinical use, but their clinical role is unknown. We reviewed the clinical roles of MRAs and MRBs based on previous knowledge and as demonstrated in representative clinical trials.Steroidal MRAs,
Daisuke, Sueta, Eiichiro, Yamamoto, Kenichi, Tsujita   +2 more
openaire   +2 more sources

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

Nature Medicine, 2012
Hypertension is a cardiovascular risk factor present in over two-thirds of people over age 60 in North America; elevated blood pressure correlates with increased risk of heart attack, stroke and progression to heart and kidney failure.
Paulo Pires, Shawn B Bender, Mark Aronovitz   +2 more
exaly   +2 more sources