Results 141 to 150 of about 83,236 (271)

Response of accommodation and vergence systems to low dose atropine

Ophthalmic and Physiological Optics, EarlyView.
Abstract Purpose Few studies have comprehensively investigated the effect of low dose atropine on the binocular vision system beyond accommodative amplitude. This study examined the effect of 0.05% atropine eye drops on a range of accommodation and vergence parameters across a 10‐day period. Methods Twenty myopic, adult participants (mean age [SD] 22.3
Emily C. Woodman‐Pieterse, Rohan P. J. Hughes, Shelley Hopkins, Alice F. Cunningham, Jana Niemand, Bianca Romeo, Natasha L. Westcott   +6 more
wiley   +1 more source

Intraocular Pressure Increase Induced by 0.5% Tropicamide‐0.5% Phenylephrine in Dogs: An Analysis of Causes Using Ultrasound Biomicroscopy

Veterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To determine whether the differences in intraocular pressure (IOP) change after the topical application of 0.5% tropicamide and 0.5% phenylephrine (TP) are due to anatomical variations in the anterior chamber using ultrasound biomicroscopy (UBM).
Donghee Kim, Sang‐Eun Park, Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Soohyun Kim, Kyung‐Mee Park   +6 more
wiley   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

Experimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz, Yavuz Erden, Çiğdem Tekin, Suat Tekin   +3 more
wiley   +1 more source

Imposed expiratory resistance, dynamic hyperinflation and locomotor power and fatigue

Experimental Physiology, EarlyView.
Abstract Expiratory flow limitation results in dynamic hyperinflation, dyspnoea and premature exercise intolerance. We aimed to measure whether expiratory resistance reduces locomotor power via limiting maximal voluntary motor activity, exacerbating muscle fatigue, or both.
Jonathan Cunha, Antoinette Domingo, Fred W. Kolkhorst, Harry B. Rossiter, Daniel T. Cannon   +4 more
wiley   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Risk of diabetes mellitus with olanzapine compared to clozapine: A systematic review and meta‐analysis

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Olanzapine and clozapine are second‐generation antipsychotics commonly associated with metabolic side effects. In Japan, olanzapine is designated as “principally contraindicated” for patients with diabetes, while clozapine is “used with caution,” despite similar pharmacological profiles.
Keigo Onda, Rizal Ichwansyah, Shuken Boku   +2 more
wiley   +1 more source

Fentanyl Disrupts Vagal Control of Airway Tone to Induce Transient Obstruction

Acta Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the primary cause of death in opioid overdose, resulting from both suppressed respiratory rhythm and increased airway and thoracic rigidity that compromise ventilation and resuscitation. While the effect(s) of opioids on central rhythm‐generating circuits are well documented, the mechanisms ...
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Nicholas J. Burgraff   +3 more
wiley   +1 more source