Results 171 to 180 of about 84,180 (270)

Anti-M3 Muscarinic Acetylcholine Receptor Autoantibody in the Serum and Saliva of Oral Lichen Planus Patients: A Case-Control Study. [PDF]

Health Sci Rep
Agha-Hosseini F, Koochaki M, Moosavi MS, Mirzaei-Dizgah I, Khayamzadeh M.   +4 more
europepmc   +1 more source

The Effect of the Anticonvulsant Topiramate on Acetylcholine‐Induced Calcium Signals is Linked to Sirt‐1 Activity

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
This work provides a potential new link between the anticonvulsive Topiramate, the deacetylase Sirt‐1 and the cholinergic signalling, suggesting that Topiramate may modulate cholinergic pathways in a Sirt‐1 depended manner. ABSTRACT Although some forms of epilepsy directly result from mutations in nicotinic acetylcholine receptors, none of the ...
Marie‐Luise Kümmel
wiley   +1 more source

Activating Muscarinic Receptor Signaling in Intrapancreatic Neurons Is Required for Parasympathetic Cholinergic Control of Pancreatic Cell Function. [PDF]

Diabetes
Levi NJ, Tamayo Garcia A, Sokolov M, Barro-Soria R, Caicedo A.   +4 more
europepmc   +1 more source

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

Angewandte Chemie International Edition, Volume 65, Issue 18, 27 April 2026.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Xanomeline-Trospium Chloride as a New Paradigm in the Treatment of Schizophrenia Through Muscarinic Modulation: A Renewed Hope in Psychiatric Care. [PDF]

Cureus
Raza M, Kaur J.
europepmc   +1 more source

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia. [PDF]

Front Pharmacol
Żełabowski K, Pichowicz W, Dembowska J, Szwajkowski M, Mykhailova D, Wurm G, Biedka K, Błaszczyk K, Piotrowski P.   +8 more
europepmc   +1 more source

Bidirectional Modulation of Beam Traversal Performance by Acetylcholine in the Cerebellar Nuclei. [PDF]

J Neurosci
Iosif CI, Drake RAR, Apps R, Bashir ZI, Pickford J.   +4 more
europepmc   +1 more source

Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review. [PDF]

Molecules
Kukla J, Olejnik P, Kasarełło K.
europepmc   +1 more source

Atropine Eye Drops in Childhood Myopia Control: A Review. [PDF]

Int J Med Sci
Zhu Q, Chen Y, Li X, Xue L, Zhang X, Zhou G, Zhou Y, Zhang J, Wilde A, Zhu Y, Li Y.   +10 more
europepmc   +1 more source