Results 11 to 20 of about 197,147 (332)
New antagonist agents of neuropeptide y receptors [PDF]
Química Nova, 2000 In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity.
Ignacio Aldana +8 more
doaj +5 more sources
Cell Communication and Signaling, 2020 Background A sensitive balance between receptor activation and desensitization is crucial for cellular homeostasis. Like many other GPCR, the human neuropeptide Y2 receptor (hY2R) undergoes ligand dependent activation and internalization into ...
Isabelle Ziffert +4 more
doaj +1 more source
PET Imaging of the Neuropeptide Y System: A Systematic Review
Molecules, 2022 Neuropeptide Y (NPY) is a vastly studied biological peptide with numerous physiological functions that activate the NPY receptor family (Y1, Y2, Y4 and Y5).
Inês C. F. Fonseca +3 more
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Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling
eLife, 2020 Neuropeptide signalling systems comprising peptide ligands and cognate receptors are evolutionarily ancient regulators of physiology and behaviour.
Luis Alfonso Yañez-Guerra +7 more
doaj +1 more source
Neuropeptide Y Is an Immunomodulatory Factor: Direct and Indirect
Frontiers in Immunology, 2020 Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in regulating a variety of biological processes, including food intake, energy metabolism, and emotional expression.
Wei-can Chen +5 more
semanticscholar +1 more source
Neurobiology of Disease, 2012 We recently demonstrated that recombinant adeno-associated viral vector-induced hippocampal overexpression of neuropeptide Y receptor, Y2, exerts a seizure-suppressant effect in kindling and kainate-induced models of epilepsy in rats.
Casper R. Gøtzsche +8 more
doaj +1 more source
Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells [PDF]
, 2018 Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular and angiogenic powerful activity is strictly associated to platelets,
Bordin, Antonella +13 more
core +2 more sources
Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest [PDF]
, 2018 Hylobius abietis (Linnaeus), or large pine weevil (Coleoptera, Curculionidae), is a pest of European coniferous forests. In order to gain understanding of the functional physiology of this species, we have assembled a de novo transcriptome of H. abietis,
Davies, Shireen-Anne +7 more
core +1 more source
Identification of neuropeptides and neuropeptide receptor genes in Phauda flammans (Walker)
Scientific Reports, 2022 Neuropeptides and neuropeptide receptors are crucial regulators to insect physiological processes. The 21.0 Gb bases were obtained from Illumina sequencing of two libraries representing the female and male heads of Phauda flammans (Walker) (Lepidoptera ...
Hai-Pan Wu +5 more
doaj +1 more source
Frontiers in Neural Circuits, 2022 Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate various biological effects including membrane excitability, synaptic transmission and synaptogenesis, gene expression, and glial cell architecture and function. To date,
Sanne M. Casello +9 more
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