Results 121 to 130 of about 205,018 (263)

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Receptor architecture of the macaque lateral geniculate nucleus. [PDF]

Brain Struct Funct
Saito M, Rapan L, Niu M, Zhao L, Tsujimura SI, Takemura H, Palomero-Gallagher N.   +6 more
europepmc   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors. [PDF]

Autism Res
Tarchi L, Doose A, Hennig J, Bernardoni F, King JA, Pisano T, Pisano T, Castellini G, Ricca V, Kamp-Becker I, Ehrlich S.   +10 more
europepmc   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Organization of neuropeptide systems in the human brain. [PDF]

Nat Neurosci
Ceballos EG, Farahani A, Liu ZQ, Milisav F, Hansen JY, Dagher A, Misic B.   +6 more
europepmc   +1 more source

Altered Habenula Resting-State Functional Connectivity and Spatial Associations with Neurotransmitter Receptor Distribution of Major Depressive Disorder with and without Anhedonia. [PDF]

Neuropsychiatr Dis Treat
Luo X, Wu Y, Yuan L, Wang Y, Li J, Xu P, Lian J, Liu X, Shen Z.   +8 more
europepmc   +1 more source

Alterations in the Components of the GABA-Glutamate System During ZIKV Infection: A Neuroscience Approach. [PDF]

Int J Mol Sci
Rengifo AC, Naizaque J, Santamaría G, Alvarez-Díaz DA, Rodriguez AV, Guío-Vega G, Rivera J, Castro CE, Dueñas Z, Torres-Fernández O.   +9 more
europepmc   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Alzheimer's disease drug development pipeline: 2026. [PDF]

Alzheimers Dement (N Y)
Cummings JL, Zhou Y, Yang Y, Zhong K, Fonseca J, Osse AL, Cheng F.   +6 more
europepmc   +1 more source