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Neurotransmitter receptor plasticity in aging
Life Sciences, 1994Neurotransmitter receptor plasticity is an important part of the compensatory processes by which the central nervous system adapts to pathological insult, long-term exposure to drugs or neuronal loss with advanced age. Receptor plasticity can be manifest as changes in the number of receptors (i.e., up- or down-regulation), changes in expression of mRNA
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The Cytoskeleton and Neurotransmitter Receptors
1996The neuronal cytoskeleton consists of microtubules and microfilaments that can interact with membrane proteins including neurotransmitter receptors and ion channels. Ligand-gated ion channels, such as nicotinic acetylcholine receptors, glycine receptors, glutamate receptors and gamma-aminobutryic acidA (GABAA) receptors, are known to cluster in plasma ...
V J, Whatley, R A, Harris
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Multiple Neurotransmitter Receptors
Journal of Neurochemistry, 1980S H, Snyder, R R, Goodman
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Receptors, Neurotransmitters and Drug Responses
New England Journal of Medicine, 1979ABNORMALITIES in sensitivity to endogenous hormones and neurotransmitters as well as to exogenous drugs pervade clinical medicine.
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Inborn errors of neurotransmitter receptors
Journal of Inherited Metabolic Disease, 1999AbstractInborn errors of neurotransmitter receptors are recently described gene mutations that directly affect receptor function. Currently three conditions are known to be caused by this mechanism: hyperekplexia; two forms of congenital inherited myasthenic syndromes; and autosomal dominant nocturnal frontal lobe epilepsy.
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Understanding neurotransmitter receptors:
Essays in Biochemistry, 1998Neurotransmitter receptor proteins can be divided into GPCRs and ligand-gated ion channels. Members within each family utilize a similar signalling mechanism and are structurally related. Multiple receptor subtypes are expressed for individual neurotransmitters, generating orders of complexity that have been exploited for therapeutic intervention ...
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Neurotransmitter Receptors: Molecular Pharmacology of Neurotransmitter Receptors.
Science, 1983openaire +2 more sources