Results 91 to 100 of about 2,915 (172)

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors

Anais da Academia Brasileira de Ciências, 2002
Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be ...
TORRÃO ANDRÉA S., BRITTO LUIZ R.G.
doaj  

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy

WIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 1, January/February 2023., 2023
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa, Izadora Rossi, Mahamed Abdullahi, Marcel Ivan Ramirez, Dan Stratton, Jameel Malhador Inal   +5 more
wiley   +1 more source

Evolution of vertebrate nicotinic acetylcholine receptors

BMC Evolutionary Biology, 2019
Background Many physiological processes are influenced by nicotinic acetylcholine receptors (nAChR), ranging from neuromuscular and parasympathetic signaling to modulation of the reward system and long-term memory.
Julia E. Pedersen, Christina A. Bergqvist, Dan Larhammar   +2 more
doaj   +1 more source

The surface accessibility of α-bungarotoxin monitored by a novel paramagnetic probe [PDF]

arXiv, 2011
The surface accessibility of {\alpha}-bungarotoxin has been investigated by using Gd2L7, a newly designed paramagnetic NMR probe. Signal attenuations induced by Gd2L7 on {\alpha}-bungarotoxin C{\alpha}H peaks of 1H-13C HSQC spectra have been analyzed and compared with the ones previously obtained in the presence of GdDTPA-BMA. In spite of the different
arxiv  

In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure

ESC Heart Failure, EarlyView.
Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke, Paulina Dißmann, Norbert Frey, Oliver J. Müller, Hatim Seoudy, Johanne Frank, Derk Frank, Martina E. Spehlmann   +7 more
wiley   +1 more source

Low household income and income volatility increase risk of lung cancer: A nationwide retrospective cohort study

Cancer Communications, EarlyView.
Chiwook Chung, Dong Wook Shin, Kyu Na Lee, Sei Won Lee, Kyungdo Han   +4 more
wiley   +1 more source

Non‐Classical Nitrogen Promoters for Rhodium‐Catalyzed Reductive Hydroformylation: New Efficient Way to Access Polyols From Linseed Oil

European Journal of Lipid Science and Technology, EarlyView.
The reductive hydroformylation of linseed oil was carried out using a rhodium precursor associated with various nitrogen derivatives such as pyridines, imidazoles, trialkylamines, amidines, and guanidines. ABSTRACT The reductive hydroformylation reaction of polyunsaturated linseed oil using a rhodium precursor associated with a nitrogen compound from ...
Walid Abdallah, Michel Ferreira, Sylvain Laclef, David Mathiron, Serge Pilard, Rénato Froidevaux, Maxime De Sousa Lopes Moreira, Hervé Bricout, Eric Monflier, Sébastien Tilloy   +9 more
wiley   +1 more source

E‐cigarette use and the relationship to smoking among Aboriginal and Torres Strait Islander and non‐Indigenous Australian Secondary Students, 2017

Australian and New Zealand Journal of Public Health, Volume 46, Issue 6, Page 807-813, December 2022., 2022
Abstract Objective: Estimate the prevalence of e‐cigarette use (vaping) among Aboriginal and Torres Strait Islander adolescents and explore the relationship between vaping and tobacco use. Methods: N=18,199 students aged 12–17 years (n=1,097 Aboriginal and Torres Strait Islander) participating in the 2017 Australian Secondary Students’ Alcohol and Drug
Christina Heris, Maree Scully, Catherine Chamberlain, Victoria White   +3 more
wiley   +1 more source