Results 151 to 160 of about 2,394,761 (293)

The Supportive Effect of Acarbose to Orlistat in Weight Management—A Randomized, Double‐Blind, Multiarm Phase 2 Trial

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the added effect of acarbose to orlistat on relative weight loss in the novel antiobesity medication EMP16. Methods In this 6‐month double‐blind trial, 240 individuals with obesity or overweight and comorbidities were randomized equally into three groups: (1) EMP16 (120 mg modified release orlistat/40 mg ...
Ulf Holmbäck, Stefan Grudén, Sandra Kuusk, Helena Litorp, Joakim Englund, Arvid Söderhäll, Göran Alderborn, Anders Forslund   +7 more
wiley   +1 more source

Preoperative Care Clinic Improves Survival for Patients Undergoing Free‐Flap Reconstruction

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This study aims to evaluate whether perioperative care improves postoperative outcomes for head and neck reconstruction patients with preexisting health conditions. Study Design Retrospective cohort study. Setting Single tertiary academic center between 2013 and 2021. Methods This study included adult patients who underwent free‐flap
Randall J. Harley, Stephen A. Esper, Tracy Z. Cheng, Soukaina Eljamri, Preetha Velu, Mario G. Solari, Shaum S. Sridharan, Mark Kubik, Seungwon Kim   +8 more
wiley   +1 more source

Editorial: Mechanisms of cholinergic transmission in motivation and cognition. [PDF]

Front Mol Neurosci
Francis TC, Klawonn AM.
europepmc   +1 more source

Nicotine Persistently Activates Ventral Tegmental Area Dopaminergic Neurons via Nicotinic Acetylcholine Receptors Containing α4 and α6 Subunits

Molecular Pharmacology, 2012
Liwang Liu, Rubing Zhao-Shea, J. McIntosh, P. Gardner, A. Tapper   +4 more
semanticscholar   +1 more source

Prospective of indigenous African wild food plants in alleviation of the severe iron deficiency anaemia in Sub‐Saharan Africa

PLANTS, PEOPLE, PLANET, EarlyView.
Iron deficiency anaemia remains a major public health challenge in Sub‐Saharan Africa, where population growth, displacement and limited resources heighten nutritional insecurity. We compiled a list of indigenous African underutilized wild food plants and examined their potential for addressing micronutrient deficiencies.
Eltayb Abdellatef, Yohannes Gedamu Gebre, Petra Bauer   +2 more
wiley   +1 more source

Cerebral Blood Flow Responses to Trigeminal Olfactory Stimulation and Their Nicotinic Cholinergic Regulation in Anesthetized Rats. [PDF]

Eur J Neurosci
Morihara D, Moriya J, Kagitani F, Uchida S.   +3 more
europepmc   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Pest Management Science, EarlyView.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis, Alexandra M. Haase, Joseph S. Tourtois, Daniel L. Hulbert, Rachel E. Cornell, Brian T. DeVree, Cadence J. Flohrschutz, Lucille M. Bell, Daniel C. Peck, Trang T. Nguyen, Lin Bao, Robert M. Kennedy, Kyle D. Schneider   +12 more
wiley   +1 more source

HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors. [PDF]

Npj Viruses
Yeasmin S, Sharma K, Nicolet C, DeCristofano L, Ataian Y, Ranjit A, Aghazadeh-Habashi A, Xu D, Schulte M.   +8 more
europepmc   +1 more source

Malignancies and immunoglobulin G4‐related disease

Rheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

α7-Nicotinic Acetylcholine Receptor and Mutated α-Synuclein Interact in Motor Behaviour and Nigrostriatal Dopamine-Findings With Potential Relevance for a Protective Effect of Cigarette Smoking and Parkinson's Disease. [PDF]

Eur J Neurosci
Pifl C, Wolf A, Elevado M, Scholze P.
europepmc   +1 more source