Results 141 to 150 of about 55,979 (309)
Laryngeal Dysfunction Following COVID‐19: A TriNetX Retrospective Cohort Study
COVID‐19 is associated with an increased incidence of new‐onset laryngeal dysfunction, including chronic cough, dysphagia, voice disorders, vocal fold paralysis, and laryngeal spasm, compared with uninfected controls. Risk peaks one to two years after infection for most outcomes and is influenced by factors such as hospitalization, mechanical ...
Cali Loblundo +4 more
wiley +1 more source
Structural rearrangements and subunit interactions in P2X receptors
P2X receptors represent the third superfamily of ligand gated ion channels with ATP as their natural ligand. Most of the mammalian P2X receptors are non-selective cation channels, which upon activation, mediate membrane depolarization and have ...
Bhargava, Yogesh, Bhargava, Y.
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Mechanisms of modulation of nicotinic acetylcholine receptors [PDF]
Dissertation (Ph.D.) University of Alaska Fairbanks, 2016Inappropriate expression of nicotinic acetylcholine receptors in the central nervous system is associated with nicotine addiction, Alzheimer's disease, Parkinson's disease and other disorders ...
Demmerly, Arianna L.
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Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
G protein-coupled receptor (GPR)109A (HM74A) is a G(i) protein-coupled receptor, which is activated by nicotinic acid (NA), a lipid-lowering drug.
Kostylina, G +9 more
core +1 more source
Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian +4 more
wiley +1 more source
ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku +4 more
wiley +1 more source
Rigid analogs of DMPP as probes for the nicotinic receptors
Chemical manipulation of the nicotinic DMPP, endowed with modest activity on the central receptors, definitely improved its affinity and pharmacokinetic properties.
MARTINI E +4 more
core +1 more source
Selective Excitation of Subtypes of Neocortical Interneurons by Nicotinic Receptors
The cellular mechanisms by which neuronal nicotinic cholinergic receptors influence many aspects of physiology and pathology in the neocortex remain primarily unknown.
Bertrand Lambolez +5 more
core +1 more source
This study examined the relative contributions of modifiable risk factors to cardiovascular diseases in adults with hypertension. More favorable risk factor profiles were consistently associated with lower risks across all outcomes. Beyond blood pressure, nicotine exposure showed comparatively larger population attributable fractions.
Shengtao Wei +10 more
wiley +1 more source
The activation mechanism of alpha 1 homomeric glycine receptors
The glycine receptor mediates fast synaptic inhibition in the spinal cord and brainstem. Its activation mechanism is not known, despite the physiological importance of this receptor and the fact that it can serve as a prototype for other homopentameric ...
Sivilotti, LG +3 more
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