Results 141 to 150 of about 55,979 (309)

Laryngeal Dysfunction Following COVID‐19: A TriNetX Retrospective Cohort Study

open access: yesThe Laryngoscope, EarlyView.
COVID‐19 is associated with an increased incidence of new‐onset laryngeal dysfunction, including chronic cough, dysphagia, voice disorders, vocal fold paralysis, and laryngeal spasm, compared with uninfected controls. Risk peaks one to two years after infection for most outcomes and is influenced by factors such as hospitalization, mechanical ...
Cali Loblundo   +4 more
wiley   +1 more source

Structural rearrangements and subunit interactions in P2X receptors

open access: yes, 2009
P2X receptors represent the third superfamily of ligand gated ion channels with ATP as their natural ligand. Most of the mammalian P2X receptors are non-selective cation channels, which upon activation, mediate membrane depolarization and have ...
Bhargava, Yogesh, Bhargava, Y.
core  

Mechanisms of modulation of nicotinic acetylcholine receptors [PDF]

open access: yes, 2016
Dissertation (Ph.D.) University of Alaska Fairbanks, 2016Inappropriate expression of nicotinic acetylcholine receptors in the central nervous system is associated with nicotine addiction, Alzheimer's disease, Parkinson's disease and other disorders ...
Demmerly, Arianna L.
core  

Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)

open access: yes, 2008
G protein-coupled receptor (GPR)109A (HM74A) is a G(i) protein-coupled receptor, which is activated by nicotinic acid (NA), a lipid-lowering drug.
Kostylina, G   +9 more
core   +1 more source

Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian   +4 more
wiley   +1 more source

Higher Increases in Plasma n‐3 Polyunsaturated Fatty Acids Following Fish Oil Supplementation in Postmenopausal Females Compared With Age‐Matched Males

open access: yesLipids, EarlyView.
ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku   +4 more
wiley   +1 more source

Rigid analogs of DMPP as probes for the nicotinic receptors

open access: yes, 2005
Chemical manipulation of the nicotinic DMPP, endowed with modest activity on the central receptors, definitely improved its affinity and pharmacokinetic properties.
MARTINI E   +4 more
core   +1 more source

Selective Excitation of Subtypes of Neocortical Interneurons by Nicotinic Receptors

open access: yes, 1999
The cellular mechanisms by which neuronal nicotinic cholinergic receptors influence many aspects of physiology and pathology in the neocortex remain primarily unknown.
Bertrand Lambolez   +5 more
core   +1 more source

Prioritizing Modifiable Risk Factors for Cardiovascular Diseases in Adults With Hypertension: A Prospective Cohort Study

open access: yesMed Research, EarlyView.
This study examined the relative contributions of modifiable risk factors to cardiovascular diseases in adults with hypertension. More favorable risk factor profiles were consistently associated with lower risks across all outcomes. Beyond blood pressure, nicotine exposure showed comparatively larger population attributable fractions.
Shengtao Wei   +10 more
wiley   +1 more source

The activation mechanism of alpha 1 homomeric glycine receptors

open access: yes, 2004
The glycine receptor mediates fast synaptic inhibition in the spinal cord and brainstem. Its activation mechanism is not known, despite the physiological importance of this receptor and the fact that it can serve as a prototype for other homopentameric ...
Sivilotti, LG   +3 more
core  

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