Results 151 to 160 of about 599,334 (260)

Genetic Basis of Tobacco Use Disorder. [PDF]

Genes (Basel)
Gervasini G.
europepmc   +1 more source

Cool but not harmless: synthetic cooling agents enhance nicotine reinforcement via the mesolimbic dopamine system. [PDF]

Neuropsychopharmacology
Amir Bishara M, de Guglielmo G.
europepmc   +1 more source

Sleep‐Autonomic Interactions in Parkinson's Disease and Multiple System Atrophy: A Comparative Study Using Structural Equation Modeling

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin, Yoonkyung Lee, Seungho Lee, Byeol‐A Yoon, Young Jin Jeong, Sang‐Myung Cheon   +5 more
wiley   +1 more source

Neuropharmacology of Nicotine Addiction and Therapeutic Strategies for Smoking Cessation. [PDF]

Biology (Basel)
Hefny AA, Karuturi RC, Kalyaanamoorthy S, Rao PPN, Ganesan A.   +4 more
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Association of Depression and Anxiety With Postoperative Complications After Septoplasty With Turbinoplasty

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Evaluate the association between comorbid depression and anxiety and postoperative complications following septoplasty with turbinoplasty, and assess whether treatment of these conditions influences surgical outcomes. Study Design Retrospective cohort study with propensity‐score matched analysis. Setting Multi‐institutional database
Amala Nayak, Iman Adibi, Suhas Rao Velichala, Michael F. Armstrong, Theodore Schuman   +4 more
wiley   +1 more source

Molecular Mechanisms of Seizure Gating in Sleep-Related Epilepsy: Genes, Channels, Sleep Stages and Circadian Rhythm. [PDF]

Curr Issues Mol Biol
Yetkin O, Baykan B, Zarowski M.
europepmc   +1 more source

Integrating bioassays and transcriptomics to detect neonicotinoid resistance in Australian Bemisia tabaci MEAM1

Pest Management Science, EarlyView.
The Bemisia tabaci MEAM1 strain GR15‐1R shows partial resistance to neonicotinoids (bottom), which correlates with an increased expression of the P450 gene CYP6CM1 compared to the insecticide‐susceptible strain SU07‐1 (top). Abstract BACKGROUND Bemisia tabaci MEAM1 is a highly invasive and polyphagous pest species of agricultural and horticultural ...
Cao (Grace) Fang, Jacob Balzer, Michael Frese, Wee Tek Tay, Tom Walsh, Jamie Hopkinson   +5 more
wiley   +1 more source

A new framework for nicotinic receptor-targeted therapeutic strategies in psychiatric and neurodegenerative disorders. [PDF]

Front Cell Neurosci
Oudaha K, Causeret F, Koukouli F.
europepmc   +1 more source

Rapid evolution and genetic basis of spinetoram resistance in Phthorimaea absoluta: evidence from six years of monitoring and laboratory selection

Pest Management Science, EarlyView.
Resistance to spinetoram in Phthorimaea absoluta is rapidly selected and functionally recessive at field‐relevant concentrations. Metabolic detoxification contributes partially, while cross‐resistance to spinosad and increased susceptibility to diamides and isoxazolines highlight practical options for resistance monitoring and insecticide rotation ...
Teófilo P. Langa, Vitor Quintela, Marcos de Oliveira, Herbert A. A. Siqueira   +3 more
wiley   +1 more source