Results 151 to 160 of about 91,068 (205)
Synchronous activation of striatal cholinergic interneurons induces local serotonin release. [PDF]
Matityahu L +6 more
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The role of Aß-peptide on spatial memory, EEG, auditory evoked potential and nicotinic cholinergic receptors in A/P transgenic mice (Amyloidi ß-peptidin osuus Alzheimerin taudin mallina käytettävien A/P siirtogeenisten hiirten paikkamuistihäiriössä, EEG- ja kuuloherätevastelöydöksissä sekä kolinergisissa nikotiinireseptoreissa tavatuissa muutoksissa) [PDF]
Wang, Jun
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Schizophrenia and Nicotinic Receptors
Harvard Review of Psychiatry, 1994Patients with schizophrenia often cannot respond to important features of their environment and filter out irrelevant stimuli. This dysfunction could be related to an underlying defect in inhibition--i.e., the brain's ability to alter its sensitivity to repeated stimuli. One of the neuronal mechanisms responsible for such inhibitory gating involves the
Robert Freedman +13 more
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Nicotinic receptors and schizophrenia
Current Medical Research and Opinion, 2004The incidence of smoking is very high in non-schizophrenic subjects presenting various psychiatric disorders (35 to 54%). However, the incidence of smoking is extremely high in schizophrenic patients: 80% to 90%, versus 25% to 30% of the general population. Various studies have demonstrated that the use of tobacco transiently restores the schizophrenic
Nadège, Ripoll +2 more
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Clinical Neuropharmacology, 1991
The causative factor(s) of Alzheimer's disease (AD) are presently unknown. However, it has been shown that the number as well as the fraction of high- to low-affinity nicotine binding sites is altered in patients suffering from this disease. This finding, along with the identification of seven genes which code for nicotinic receptors expressed in the ...
S. Heinemann +11 more
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The causative factor(s) of Alzheimer's disease (AD) are presently unknown. However, it has been shown that the number as well as the fraction of high- to low-affinity nicotine binding sites is altered in patients suffering from this disease. This finding, along with the identification of seven genes which code for nicotinic receptors expressed in the ...
S. Heinemann +11 more
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Nicotinic Acetylcholine Receptors
2003Publisher Summary This chapter deals with nicotinic acetylcholine receptors. Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction. As ionotropic receptors, nAChRs are directly linked to ion channels
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Nicotinic Receptors and Attention
2015Facilitation of different attentional functions by nicotinic acetylcholine receptor (nAChR) agonists may be of therapeutic potential in disease conditions such as Alzheimer's disease or schizophrenia. For this reason, the neuronal mechanisms underlying these effects have been the focus of research in humans and in preclinical models.
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Structure of Neuronal Nicotinic Receptors
2015Nicotinic acetylcholine receptors (nAChRs) are a critical component of the brain's cholinergic neurotransmission system that modulates important physiological processes and whose dysfunction has been observed in patients with neurodegenerative diseases and mental illness.
Fasoli F, Gotti C
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