Results 151 to 160 of about 55,979 (309)

Associations Between Cumulative Head Trauma and Self‐Reported Parkinsonism and Parkinson's Disease in Former Soccer Players

open access: yesMovement Disorders, EarlyView.
Abstract Background Cumulative head trauma, encompassing repetitive head impacts (RHI) and traumatic brain injury (TBI), has been associated with later‐life neurodegenerative disease. Studies on parkinsonism/Parkinson's disease (PD) have evaluated RHI and TBI in isolation, yielding mixed results.
Annalise E. Miner   +14 more
wiley   +1 more source

A new specific neuronal modulatory effect of nicotine: the functional cross talk between nicotinic and glutamate receptors

open access: yes, 2014
We here have addressed the topic of the cross-talk between receptors. We provide evidence supporting the co-localization and the functional interaction between nicotinic acetylcholine receptors and some glutamatergic receptors.
Mario Marchi, Anna Pittaluga, Massimo Grilli
core  

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen   +5 more
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

open access: yesPest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks   +3 more
wiley   +1 more source

Assessing the potential for insecticide cross‐resistance to a novel insecticide in the Colorado potato beetle (Leptinotarsa decemlineata) using phenotypic and transcript expression analysis

open access: yesPest Management Science, EarlyView.
Phenotypic and transcriptional responses to imidacloprid and isocycloseram were examined across U.S. populations of the Colorado potato beetle, showing evidence of phenotypic cross‐resistance alongside population‐level variation in detoxification gene expression.
Emma E. Terris   +6 more
wiley   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

open access: yesSmart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding   +8 more
wiley   +1 more source

Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro‐Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe   +2 more
wiley   +1 more source

Nicotine as an odorant : a biochemical and electrophysiological study of receptors for nicotine in the olfactory epithelium of the rat [PDF]

open access: yes
The results suggest that nicotine vapour stimulates an in vitro olfactory preparation in three strains of rat and two strains of mouse, in a manner similar to known odorants.
Edwards, Damian Andrew
core  

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