Results 241 to 250 of about 2,394,761 (293)

The endogenous cholinergic system overwhelmingly predominates over the exogenous system in regulating ventricular bioelectrical homeostasis. [PDF]

Eur Heart J
Xie D, Liu Y, Chen YH.
europepmc   +1 more source

α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer. [PDF]

Biomolecules
Feng X, Tian Y, Guo X, Lei JH, Yu J, Zheng C, Chen M, Ding RB, Kwok HF, Luo S, Bao J.   +10 more
europepmc   +1 more source

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Schizophrenia and Nicotinic Receptors

Harvard Review of Psychiatry, 1994
Patients with schizophrenia often cannot respond to important features of their environment and filter out irrelevant stimuli. This dysfunction could be related to an underlying defect in inhibition--i.e., the brain's ability to alter its sensitivity to repeated stimuli. One of the neuronal mechanisms responsible for such inhibitory gating involves the
Merilyne Waldo, Josette G. Harris, Herbert T. Nagamoto, Sherry Leonard, Lawrence E. Adler, Robert Freedman, Marina Myles-Worsley, C. Munro Cullum, William Byerley, Christine L. Miller, Paula C. Bickford, Hilary Coon, Jay M. Griffith, Greg M. Rose   +13 more
openaire   +3 more sources

The Nicotinic Receptor Genes

Clinical Neuropharmacology, 1991
The causative factor(s) of Alzheimer's disease (AD) are presently unknown. However, it has been shown that the number as well as the fraction of high- to low-affinity nicotine binding sites is altered in patients suffering from this disease. This finding, along with the identification of seven genes which code for nicotinic receptors expressed in the ...
S. Heinemann, J. Boulter, J. Connolly, E. Deneris, R. Duvoisin, M. Hartley, I. Hermans-Borgmeyer, M. Hollmann, A. OʼShea-Greenfield, R. Papke, S. R ogers, J. Patrick   +11 more
openaire   +3 more sources

Nicotinic receptors and schizophrenia

Current Medical Research and Opinion, 2004
The incidence of smoking is very high in non-schizophrenic subjects presenting various psychiatric disorders (35 to 54%). However, the incidence of smoking is extremely high in schizophrenic patients: 80% to 90%, versus 25% to 30% of the general population. Various studies have demonstrated that the use of tobacco transiently restores the schizophrenic
Nadège Ripoll, Marie Bronnec, Michel Bourin   +2 more
openaire   +3 more sources

Review: Nicotinic receptors and stages of nicotine dependence

Journal of Psychopharmacology, 2009
Smoking is one of the leading causes of preventable death, where nicotine has been identified as the primary addictive constituent of tobacco. Consequently, there have been extensive investigations into the neuroadaptations that occur as nicotine dependence develops, where numerous neurological systems have been implicated. The focus of this review was
Rodney A. Lea, Penelope Truman, KA Brennan, PS Fitzmaurice   +3 more
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Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders

Current Topics in Medicinal Chemistry, 2004
Advances in the understanding of the neurobiology of the nicotinic receptor have started to be matched by an appreciation of the potential role of these receptors in a variety of neuropsychiatric disorders. While alterations in nicotinic receptor number and/or function have been associated with such conditions as Alzheimer's disease for several years ...
Alexandra Potter, Abhay Singh, Paul A. Newhouse   +2 more
openaire   +3 more sources