Abstract Background and aims Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low.
Carol‐Ann Getty +2 more
wiley +1 more source
Semi-synthesis in the exploration of opioid-targeting natural products.
Riley AP.
europepmc +1 more source
Opioid Affinity of Diazacyclic Peptidomimetic Compounds Derived from Reduced Polyamides. [PDF]
Chaudhari P +4 more
europepmc +1 more source
Drug use among people in prison: A global review of epidemiology, harms and interventions
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley +1 more source
Effect of Oliceridine on Sufentanil-Induced Cough During General Anesthesia: A Prospective Randomized Controlled Clinical Study. [PDF]
Gong WY +6 more
europepmc +1 more source
Abstract Aims This study sought to validate a community‐acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood‐borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual ...
Brendan Clifford +9 more
wiley +1 more source
Single-cell transcriptomics reveals probiotic reversal of neonatal morphine-induced gene disruptions underlying adolescent pain hypersensitivity. [PDF]
Tao J +6 more
europepmc +1 more source
Exploring the genetic overlap between substance use disorder and educational attainment
Abstract Background and aims Substance use disorder (SUD) is a polygenic psychiatric condition characterized by persistent drug use despite negative consequences. Several studies support that higher cognitive performance and educational attainment (EA) are associated with a reduced risk for SUD.
Judit Cabana‐Domínguez +16 more
wiley +1 more source
Association of Galanin and Its Receptor Gene Polymorphism with Opioid Dependence: Preliminary Findings from India. [PDF]
Naz I +6 more
europepmc +1 more source
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden +10 more
wiley +1 more source

