Results 31 to 40 of about 479 (208)

Does induction or augmentation of labor increase the risk of postpartum hemorrhage in pregnant women with anemia? A multicenter prospective cohort study in India

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 299-309, April 2025.
Abstract Objective To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.
Tuck Seng Cheng   +21 more
wiley   +1 more source

Oxytocin receptor is regulated by Peg3

open access: yesPLOS ONE, 2018
Mouse Peg3 encodes a DNA-binding protein involved in the milk letdown process. In the current study, we tested whether PEG3 controls the expression of the oxytocin receptor gene. According to the results, PEG3 directly binds to a genomic region within the 3rd exon of Oxtr, which contains a DNA-binding motif for PEG3.
Wesley D. Frey   +5 more
openaire   +4 more sources

Association between patient safety culture, adverse events, and essential practices during childbirth in six Brazilian maternity hospitals

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines whether hospitals with stronger patient safety culture more consistently follow essential birth practices and have fewer adverse outcomes for mothers and newborns and whether this evidence can guide maternity care priorities in patient safety policy.
Zenewton A. S. Gama   +11 more
wiley   +1 more source

Pyrazolsulfonamide Agonists of Oxytocin Receptor [PDF]

open access: yesACS Medicinal Chemistry Letters, 2014
Title: Pyrazolsulfonamide Agonists of Oxytocin Receptor Patent/Patent Application Number: WO 2014/111356 A1 Publication date: July 24, 2014 Priority Application: EP 2013-151632 Priority date: January 17, 2013 Inventors: Bissantz, C.; Grundschober, C.; Nettekoven, M.; Plancher, J.-M.; Vifian, W. Assignee Company: Hoffmann-La Roche, Inc.
openaire   +2 more sources

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch   +5 more
wiley   +1 more source

Oxytocin Protects Nigrostriatal Dopamine Signal via Activating GABAergic Circuit in the MPTP‐Induced Parkinson's Disease Model

open access: yesAdvanced Science
The most pronounced neuropathological feature of Parkinson's disease (PD) is the loss of dopamine (DA) neurons in the substantia nigra compacta (SNc), which depletes striatal DA.
Yurong Wang   +8 more
doaj   +1 more source

Oxytocin in cesarean-sections. What's new?

open access: yesRevista Brasileira de Anestesiologia
Oxytocin is the uterotonic agent of choice in the prevention and treatment of postpartum uterine atony. Nevertheless, there is no consensus on the optimal dose and rate for use in cesarean sections.
Eduardo Tsuyoshi Yamaguchi   +2 more
doaj   +1 more source

Molecular Mechanisms of Oxytocin Signaling at the Synaptic Connection

open access: yesNeural Plasticity, 2018
Aberrant regulation of oxytocin signaling is associated with the etiology of neurodevelopmental disorders. Synaptic dysfunctions in neurodevelopmental disorders are becoming increasingly known, and their pathogenic mechanisms could be a target of ...
Jan Bakos   +3 more
doaj   +1 more source

Cholesterol as stabilizer of the oxytocin receptor

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2002
The function of the oxytocin receptor system is strongly dependent on steroids as demonstrated by several physiological studies. One key element of this dependence on steroids may be the interaction of cholesterol and the oxytocin receptor. In this study, we show that cholesterol stabilizes the solubilized human oxytocin receptor against thermal ...
Gimpl, Gerald, Fahrenholz, Falk
openaire   +2 more sources

Balloon catheter plus concurrent vaginal misoprostol versus vaginal misoprostol alone for cervical ripening in induction of labor: A systematic review and an individual participant data meta‐analysis of randomized controlled trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Cervical ripening in labor induction using a combination of methods is gaining popularity, but the effectiveness and safety of this approach are not clear. The assessment of study trustworthiness has recently been raised for evidence synthesis.
Malitha Patabendige   +13 more
wiley   +1 more source

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