Results 151 to 160 of about 444,848 (367)

A Bio‐Inspired Perspective on Materials Sustainability

Advanced Materials, EarlyView.
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier, Khashayar Razghandi, Peter Fratzl   +2 more
wiley   +1 more source

Regulation of EGFR Degradation by Ankyrin105 [PDF]

Growth factors can regulate a variety of cellular processes by activating receptors on the cell surface. Many of the receptors belong to the receptor tyrosine kinase family, including the platelet-derived growth factor receptor and the epidermal growth ...
Li, Zhubing
core  

A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device [PDF]

, 2019
Background and objectives: Several sources of haematopoietic stem cells have been used for static culture of megakaryocytes to produce platelets in vitro.
Baruch, Dominique, Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Sicot, Geraldine, Six, Katrijn   +5 more
core   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture

Cell Communication and Signaling, 2010
Background Uterine leiomyomas (fibroids) are benign smooth muscle tumors that often contain an excessive extracellular matrix (ECM). In the present study, we investigated the interactions between human uterine leiomyoma (UtLM) cells and uterine leiomyoma-
Robboy Stanley J, Walmer David K, Kissling Grace E, Castro Lysandra, Wang Lu, Swartz Carol D, Zheng Xaiolin, Yu Linda, Moore Alicia B, Dixon Darlene   +9 more
doaj   +1 more source

Imatinib treatment of poor prognosis mesenchymal-type primary colon cancer: A proof-of-concept study in the preoperative window period (ImPACCT) [PDF]

, 2017
Background: The identification of four Consensus Molecular Subtypes (CMS1-4) of colorectal cancer forms a new paradigm for the design and evaluation of subtype-directed therapeutic strategies.
Bloemendal, H.J. (Haiko), Boerman, A.W., Borel Rinkes, I.H.M. (Inne), Brink, M.A. (Menno), Elias, S.G. (Sjoerd), Grevenstein, H.M.U. (Helma) van, Holierhoek, Y.C.W., Koopman, M. (Miriam), Kranenburg, O. (Onno), Leng, W.W.J. (Wendy) de, Lolkema, M.P. (Martijn), Mathijssen, A.H.J. (Ron), Schwartz, M.P. (Matthijs), Ubink, I., Verheijen, P.M., Weger, R.A. (Roel) de   +15 more
core   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Interaction of Oligonucleotides with Gold Nanoparticles: Factors Beyond Electrostatic and Van‐Der Waals Forces

Advanced Materials Interfaces, EarlyView.
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur, Nicola Cavallini, Debora Ferrari, Laura Fabris   +3 more
wiley   +1 more source

In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models

Neoplasia: An International Journal for Oncology Research, 2017
The fibroblast growth factor receptor (FGFR) pathway has been implicated both as an escape mechanism from anti-angiogenic therapy and as a driver oncogene in different tumor types.
Federica Guffanti, Rosaria Chilà, Ezia Bello, Massimo Zucchetti, Monique Zangarini, Laura Ceriani, Mariella Ferrari, Monica Lupi, Anne Jacquet-Bescond, Mike F. Burbridge, Marie-Jeanne Pierrat, Giovanna Damia   +11 more
doaj   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source