Results 211 to 220 of about 444,848 (367)

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo, Wen‐Ying Zheng, Qiong Zhang, Yan Yuan, Mei‐Qi Li, Kai Du, An‐Ran Gao, Li‐Jun Pei, Jie Xie, Wen‐Hao Chen, Long Zhang, Xiu‐Zhu Guo, Xiao‐Ran Yang, Chao Zeng, Guo‐Hua Yang, Min Deng   +15 more
wiley   +1 more source

Poor expression of miR‐195‐5p can assist the diagnosis of cerebral vasospasm after subarachnoid hemorrhage and predict adverse outcomes

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH patients. This study explored the clinical diagnostic value of serum miR‐195‐5p levels in CVS after SAH (SAH + CVS) and its relationship with the prognosis of SAH + CVS.
Yong Li, Senyuan Yang, Xiaobin Zhou, Runlong Lai   +3 more
wiley   +1 more source

Recent advances in TAM mechanisms in lung diseases. [PDF]

J Transl Med
Ban J, Qian J, Zhang C, Li J.
europepmc   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Platelet-rich plasma activation: are there differential effects in reproductive medicine? [PDF]

J Ovarian Res
Anitua E, de la Fuente M, Prado R, Alkhraisat MH.   +3 more
europepmc   +1 more source

A Real‐Time Cell Death Self‐Reporting Theranostic Agent for Dynamic Optimization of Photodynamic Therapy

Advanced Science, EarlyView.
A cell death self‐reporting photodynamic theranostic nanoagent (CDPN) is developed that integrates photodynamic therapy (PDT) with real‐time K⁺ imaging to provide timely feedback on treatment responses. This approach enables the optimization of the drug‐light interval (DLI), a critical factor in PDT, resulting in significantly enhanced antitumor ...
Wei Bian, Qiyue Wang, Cui He, Pan Tao, Juanjuan Zheng, Yulu Zhang, Jing Li, Fangyuan Li, Hongyan Jia, Daishun Ling   +9 more
wiley   +1 more source

Pan-cancer analysis of PDGFRB: Laying the foundation for the development of targeted immunotherapy drugs. [PDF]

Medicine (Baltimore)
Gao Q, Cui Y, Gao F, Yang Y, Huangfu W, Wang M.   +5 more
europepmc   +1 more source

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

Molecular and Cellular Biology, 1991
J. Escobedo, D. R. Kaplan, W. Kavanaugh, C W Turck, L. T. Williams   +4 more
semanticscholar   +1 more source

Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling

Advanced Science, EarlyView.
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu, Lingna Wang, Jiaqing Liu, Haitao Yuan, Kaiqing Zhang, Yun Qiu, Fangfang Zhu   +6 more
wiley   +1 more source