Results 221 to 230 of about 444,848 (367)

Advances in Regenerative Medicine for Orthopedic Injuries: A Comprehensive Review. [PDF]

Cureus
Das S, Thakur A, Datta A, Sahoo A, Bandyopadhyay S, Sah AK.   +5 more
europepmc   +1 more source

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

Advanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang, Xiaochen Gai, Yuhui Li, Zuoyu Chen, Xi Zhang, Wei Qiao, Ping Qiu, Chunyuan Du, Sufang Sheng, Jingran Hao, Yujie Zhang, Heng Fan, Xiaorong Li, Ming Liu, Jun Zhang, Zhe Pan, Yongsheng Chang   +16 more
wiley   +1 more source

The Role of Platelet Dysfunctions in the Pathogenesis of the Hemostatic-Coagulant System Imbalances. [PDF]

Int J Mol Sci
Badulescu OV, Ciocoiu M, Vladeanu MC, Huzum B, Plesoianu CE, Iliescu-Halitchi D, Bojan A, Iliescu-Halitchi C, Bojan IB.   +8 more
europepmc   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

β-blocker suppresses both tumoral sympathetic neurons and perivascular macrophages during oncolytic herpes virotherapy. [PDF]

J Immunother Cancer
Kyritsi K, Pacholczyk R, Douglass E, Yu M, Fang H, Zhou G, Kaur B, Wang Q, Munn DH, Hong B.   +9 more
europepmc   +1 more source

Engineered Bacterial Outer Membrane Vesicles Hitchhiking on Neutrophils for Antibody Drug Delivery to Enhance Postoperative Immune Checkpoint Therapy

Advanced Science, EarlyView.
This study employs neutrophils for the precise delivery of anti‐CD47 antibodies, combined with bacterial outer membrane vesicles, to enhance macrophage phagocytic function in the tumor microenvironment. This approach effectively activates T‐cell anti‐tumor immune responses and significantly reduces the risk of postoperative tumor recurrence and ...
Meng Guan, Xiao‐Ting Xie, Dong Zhou, Kai Cheng, Bin Zhang, Xin‐Yue Xu, Yong Li, Yi‐Tong Zhou, Wei Peng, Li‐Li Chen, Peng‐Shuo Dong, Si Chen, Jia‐Hua Zou, Bo Liu, Yuan‐Di Zhao, Jin‐Xuan Fan   +15 more
wiley   +1 more source

Effect of platelet-rich plasma on angiogenic and regenerative properties in patients with critical limb ischemia. [PDF]

Regen Ther
Tanzadehpanah H, Nobari S, Hoseini AJ, Ghotbani F, Mehrabzadeh M, Jalili Shahri J, Alipour A, Sheykhhasan M, Manoochehri H, Darroudi S, Mahaki H.   +10 more
europepmc   +1 more source

Dry Battery Electrode Technology: From Early Concepts to Industrial Applications

Advanced Energy Materials, EarlyView.
This review highlights dry battery electrode coating as a promising approach toward environmentally friendly and efficient battery electrode production. It focuses on polytetrafluoroethylene binder based dry film methods and summarizes the historical background, recent developments for lithium‐Ion and next‐generation batteries, as well as approaches ...
Benjamin Schumm, Arthur Dupuy, Milena Lux, Christian Girsule, Susanne Dörfler, Florian Schmidt, Magdalena Fiedler, Maria Rosner, Felix Hippauf, Stefan Kaskel   +9 more
wiley   +1 more source

TGIF1 overexpression promotes glioma progression and worsens patient prognosis

Cancer Medicine, Volume 11, Issue 24, Page 5113-5128, December 2022., 2022
This study is the first to comprehensively analyze and reveal TGIF1, as a new oncogene, is closely related to the malignancy‐related phenotype of glioma, and that TGIF1 could be an independent risk factor for poor prognosis of glioma, which is expected to become a new target for individualized treatment of glioma patients.
Baoya Wang, Qiong Ma, Xuelin Wang, Kunshan Guo, Zhendong Liu, Gang Li   +5 more
wiley   +1 more source

The Regenerative Marriage Between High-Density Platelet-Rich Plasma and Adipose Tissue. [PDF]

Int J Mol Sci
Everts PA, Podesta L, Lana JF, Shapiro G, Domingues RB, van Zundert A, Alexander RW.   +6 more
europepmc   +1 more source