Results 261 to 270 of about 444,848 (367)

Tyrosine kinase inhibitors in Ewing's sarcoma: a systematic review. [PDF]

BMC Cancer
Assi A, Farhat M, Mohanna R, Hachem MCR, Zalaquett Z, Aoun M, Farraj SA, Daher M, Sebaaly A, Kourie HR.   +9 more
europepmc   +1 more source

Absence of Functional Autoantibodies Targeting Angiotensin II Receptor Type 1 and Endothelin‐1 Type A Receptor in Circulation and Purified IgG From Patients With Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen, Eva M. Hoekstra, E. W. Nivine Levarht, Ilana B. Kotliar, Thomas P. Sakmar, René E. M. Toes, Jeska K. de Vries‐Bouwstra, Laura H. Heitman, Cynthia M. Fehres   +8 more
wiley   +1 more source

From Blood to Therapy: The Revolutionary Application of Platelets in Cancer-Targeted Drug Delivery. [PDF]

J Funct Biomater
Xie L, Gan F, Hu Y, Zheng Y, Lan J, Liu Y, Zhou X, Zheng J, Zhou X, Lou J.   +9 more
europepmc   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

Potential biomarkers for the prognosis of gastrointestinal stromal tumors. [PDF]

World J Gastrointest Oncol
Sun YF, Cao XK, Wei Q, Gao YH.
europepmc   +1 more source

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh, Cuong Tran‐Manh, Andrea‐Hermina Györfi, Nicholas Dickel, Christoph Liebel, Xiang Zhou, Jiucun Wang, Meik Kunz, Helena Arozenius, Lars Pettersson, Sam Lindgren, Christina Wenglén, Jörg H. W. Distler   +12 more
wiley   +1 more source

A Cross-Sectional Exploratory Study of Rat Sarcoid (Ras) Activation in Women with and Without Polycystic Ovary Syndrome. [PDF]

Cells
Niinuma SA, Habib H, Takemoto AS, Das P, Sathyapalan T, Atkin SL, Butler AE.   +6 more
europepmc   +1 more source

Human platelet lysate: a potential therapeutic for intracerebral hemorrhage. [PDF]

Front Neurosci
Qiu D, Wang L, Wang L, Dong Y.
europepmc   +1 more source

von Willebrand disease and angiodysplasia: a wider view of pathogenesis in pursuit of therapy. [PDF]

Haematologica
Crossette-Thambiah C, Randi AM, Laffan M.   +2 more
europepmc   +1 more source