Results 251 to 260 of about 152,856 (310)

Sex Hormones-Mediated Modulation of Immune Checkpoints in Pregnancy and Recurrent Pregnancy Loss. [PDF]

Int J Mol Sci
Zych M, Roszczyk A, Zakrzewska M, Zagożdżon R, Pączek L, Dąbrowski FA, Kniotek MJ.   +6 more
europepmc   +1 more source

Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective. [PDF]

Pharmacol Res Perspect
Fleming B, Guseinov AA, Tikhonova IG, Milligan G, Perry-Hauser NA.   +4 more
europepmc   +1 more source

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Receptors for progesterone

Gynecologic Oncology, 1974
Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
B R, Rao, W G, Wiest
openaire   +2 more sources

Progesterone and progesterone receptors in reptiles

General and Comparative Endocrinology, 2002
The role of progesterone (P) has been most extensively studied in the female reproductive tissues (ovary, reproductive tract, mammary gland) and in the brain, in which it is an important regulator and modulator in conjunction with estradiol (E). In nonmammalian vertebrate species, less work has been done on P metabolites involved in ovulation.
Noemí, Custodia-Lora, Ian P, Callard
openaire   +2 more sources

Progesterone receptor coactivators

Steroids, 2000
Progesterone action is mediated by intracellular progesterone receptors that regulate target gene transcription. Recently, numerous proteins termed coactivators have been identified that are recruited by the liganded progesterone receptor and enhance receptor-dependent transactivation.
B G, Rowan, B W, O'Malley
openaire   +2 more sources

Novel Mechanisms of Progesterone Antagonists and Progesterone Receptor

Journal of the Society for Gynecologic Investigation, 2000
The progesterone receptor (PR), as a member of the nuclear receptor superfamily of ligand-dependent transcription factors, activates gene transcription through binding to specific palindromic progesterone response elements (PRE) in the promoter region of progestin-responsive genes.
D P, Edwards, S A, Leonhardt, E, Gass-Handel   +2 more
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Progesterone antagonists and progesterone receptor modulators

Expert Opinion on Investigational Drugs, 2003
Since the discovery of the antiprogestin RU 486 (mifepristone), other compounds have been synthesised that function as pure progesterone antagonists or progesterone receptor modulators. The latter are mixed agonists-antagonists. Mifepristone is usually used to terminate pregnancy but these compounds have numerous other applications in female healthcare.
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The role of progesterone and the progesterone receptor in cancer

Expert Review of Endocrinology & Metabolism, 2017
There is an abundance of accumulating data strongly suggesting there is a key role for the progesterone receptor in the molecular events effecting the growth or containment of a variety of cancers. This knowledge should lead to novel new strategies to combat various cancers, including drugs classified as progesterone receptor modulators or monoclonal ...
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