Results 261 to 270 of about 684,032 (303)
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Activation of Progesterone Receptor by ATP
European Journal of Biochemistry, 1981Progesterone-receptor complex from freshly prepared hen oviduct cytosol acquired the ability to bind to isolated nuclei, DNA-cellulose and ATP-Sepharose when incubated with 5-10 mM ATP at 4 degrees C. The extent of this ATP-dependent activation was higher when compared with heat-activation achieved by warming the progesterone-receptor complex at 23 ...
V, Moudgil +5 more
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Progesterone Receptors in Rat Thymus
Endocrinology, 1983Tritiated promegestone ([3H]R5020) is bound with high affinity in cytosol prepared from the thymus gland of both male and female rats. To prevent tracer binding to glucocorticoid receptors, we have used excess RU26988 (11 beta, 17 beta-dihydroxy-21-methyl-17 alpha-pregna-1,4,6-trien-20-yn-3-one), a highly specific synthetic glucocorticoid.
P T, Pearce, B A, Khalid, J W, Funder
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Progesterone and the progesterone receptor.
The Journal of reproductive medicine, 2001During the 1990s, extensive research has effectively mapped the progesterone receptor-mediated actions of progesterone and has more recently uncovered nonreceptor-mediated effects--the effect of progesterone on uterine sensitivity to oxytocin, for example, involves direct, nongenomic progesterone action on the uterine oxytocin receptor.
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PROGESTERONE RECEPTORS IN BREAST CANCER
Australian and New Zealand Journal of Surgery, 1984Sixty‐six women who had received hormonal therapy for advanced disease were assessed for objective response to treatment. Another 51 patients who had received chemotherapy were similarly studied. Progesterone receptor was of no value as a predictor of patients unlikely to respond to hormone therapy, though it may have a role in predicting patients ...
R M, Bryan +5 more
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Estrogen and progesterone receptors in meningiomas
Surgical Neurology, 1986Estradiol and progesterone receptors were studied in 14 patients with meningiomas. Estrogen receptors were detected by specific monoclonal antibodies, whereas progesterone receptors were assayed by the dextran-coated charcoal method. In 9 cases the estrogen receptors were also investigated in cultured tumor cells.
MAIURI, FRANCESCO +2 more
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Progesterone Receptor in Cystosarcoma Phyllodes
Archives of Surgery, 1977A specific receptor for progesterone has been found in a cystosarcoma phyllodes, as determined by charcoal adsorption and sucrose gradient analysis. Similar assays for estrogen receptors were negative. The tumor consisted almost entirely of stroma that contained the progesterone receptors.
B R, Rao, J S, Meyer
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Journal of Steroid Biochemistry, 1979
Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Progesterone Receptor Interaction with Chromatin
2014Understanding how eukaryotic gene regulation works implies unraveling the mechanisms used by transcription factors to access DNA information packaged in chromatin. The current view is that different cell types express different parts of the genome because they are equipped with different sets of transcription factors.
Guillermo P, Vicent +5 more
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Progesterone Receptors of Chick Oviduct
1978The chick oviduct progesterone receptor has been purified to homogeneity by affinity chromatography and its molecular action studied in vitro. The native receptor is a 200,000 MW dimer of two dissimilar 4S subunits with different intranuclear function.
W T, Schrader, B W, O'Malley
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Chaperones in progesterone receptor complexes
Seminars in Cell & Developmental Biology, 2000Studying the components, pathways, and dynamics of progesterone receptor (PR) assembly with chaperones has provided a highly valuable model system for understanding the coordinate actions of chaperones. Chaperones are primarily adapted to facilitate protein folding processes, and the actions of chaperones toward PR and other steroid receptors probably ...
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