Australasian Journal of Dermatology, EarlyView.ABSTRACT Acne vulgaris is a globally prevalent dermatological disease, with its severity ranging from mild to severe. While moderate to severe acne often requires topical or systemic pharmaceutical therapy, mild to moderate acne may be managed with dermocosmetics, which are over‐the‐counter skincare agents with active ingredients that target acne ...
Ryan De Cruz +7 more
wiley +1 more source
Nuclear receptors as novel regulators that modulate cancer radiosensitivity and normal tissue radiotoxicity. [PDF]
Mol CancerMeng X, Li X, Gao Y, Zhang S.
europepmc +1 more source
Allergy, EarlyView.Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi +14 more
wiley +1 more source
A Comparative Study of a Potent CNS-Permeable RARβ-Modulator, Ellorarxine, in Neurons, Glia and Microglia Cells In Vitro. [PDF]
Int J Mol SciZhang Y +6 more
europepmc +1 more source
Andrology, EarlyView.Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert +10 more
wiley +1 more source
Vitamin D and Retinoic Acid Require Protein Kinase C Activity and Reactive Oxygen Species as Opposing Signals Regulating <i>PEIG-1</i>/<i>GPRC5A</i> Expression in Caco-2 and T84 Colon Carcinoma Cells. [PDF]
BiomoleculesIglesias González PA +3 more
europepmc +1 more source
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Effect of Retinoic Acid on the Cerebral Vasculature: Analysis of the Vasoactive Response of Smooth Muscle Cells in Normal and Ischemic Contexts. [PDF]
J XenobiotPouso MR +5 more
europepmc +1 more source
Applications of spatial transcriptomics in studying spermatogenesis
Andrology, EarlyView.Abstract Spermatogenesis is a complex differentiation process that is facilitated by a series of cellular and molecular events. High‐throughput genomics approaches, such as single‐cell RNA sequencing, have begun to enable the systematic characterization of these events. However, the loss of tissue context because of tissue disassociations in the single‐
Qianlan Xu, Haiqi Chen
wiley +1 more source
The interictal transcriptomic map of migraine without aura. [PDF]
J Headache PainPetschner P +9 more
europepmc +1 more source