Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source
Single strand conformation polymorphism (SSCP) detection in six genes in Portuguese indigenous sheep breed [PDF]
Evaluation of the genetic diversity for six genes in forty animals of the Portuguese indigenous sheep breed (Ovis aries) ""Churra da Terra Quente"" was done.
Guedes-Pinto H. +3 more
doaj
Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]
BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham +45 more
core +2 more sources
The growth hormone (GH) and growth hormone receptor (GHR) system is a central regulator of growth and metabolism in vertebrates, with critical implications for aquaculture productivity and functional genomics research.
Neethi Ajith +7 more
doaj +1 more source
Binding in vitro to rat liver receptors does not correlate with activities in vivo of bovine somatotropin. Use of chemically modified derivatives as probes [PDF]
Bovine somatotropin with an increasing number of its carboxylate groups modified by reaction with glycine methyl ester in the presence of a water-soluble carbodi-imide was tested for its activity in different bioassays. Only those derivatives which were known to be active in the body-weight-increase bioassay were able to compete with 125I-labelled ...
L P, Roguin +3 more
openaire +2 more sources
Insights into Structure-Activity Relationships of Somatostatin Analogs Containing Mesitylalanine. [PDF]
The non-natural amino acid mesitylalanine (2,4,6-trimethyl-L-phenylalanine; Msa) has an electron-richer and a more conformationally restricted side-chain than that of its natural phenylalanine counterpart.
Aragón Altarriba, Eric +12 more
core +2 more sources
Background. Oligonucleotides (OLNs) can participate in a wide range of protein-ligand interactions and perform numerous cellular functions by forming structures that enable specific interactions with DNA, RNA, and proteins, what is crucial for many biological processes.
Oleksandr Nuzhnyi +2 more
openaire +4 more sources
The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]
Peer ...
Giesemann, G. +4 more
core +2 more sources
A female survivor of childhood medulloblastoma presenting with growth-hormone-induced edema and inflammatory lesions: a case report [PDF]
Introduction The improved survival of children with brain tumors has increased concerns about treatment-related sequelae. Growth hormone deficiency is frequently observed after craniospinal irradiation for medulloblastoma.
Veronica Biassoni +7 more
core +1 more source
Lactating Holstein cows were used to assess the effect of bovine somatotropin (bST; n = 8) and fasting (FAST; n = 4) on ligand binding to beta-adrenergic (BAR) and Type-1 adenosine (A1R) receptors in adipose tissue. Cows received exogenous bST (sometribove; 40 mg/d) or no hormone (control) for 4 d in a single-reversal design with a 7-d interval between
K L, Houseknecht +3 more
openaire +2 more sources

