Identification of salvianolic acid A as an ADP receptor-selective and Gq/IP<sub>3</sub> pathway-mediated anti-platelet component in Qishen Yiqi. [PDF]
Dang W +12 more
europepmc +1 more source
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova +2 more
wiley +1 more source
Low serum transferrin predicts adverse outcome in COVID‐19 and is related to coagulation activity
British Journal of Haematology, EarlyView.
Lukas Lanser +4 more
wiley +1 more source
Out With the Old, in With the New: Age‐Related D‐Dimer Thresholds
ABSTRACT Background A fixed D‐dimer cut‐off threshold of 0.500 μg/mL is used in Blackrock Health Hermitage Clinic (BHHC) and most Haematology laboratories across Ireland, however, international guidelines have evolved over the past decade, and a growing body of evidence supports the use of age‐adjusted D‐dimer thresholds.
Ciara O'Connor +2 more
wiley +1 more source
Qiliqiangxin capsule attenuates platelet activation and thrombosis by suppressing Ca<sup>2+</sup> influx and PKC signaling. [PDF]
Han L +10 more
europepmc +1 more source
Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat +14 more
wiley +1 more source
Cellular and molecular mechanisms of thrombosis and thrombus-targeted thrombolytic strategies. [PDF]
Yu X +8 more
europepmc +1 more source
Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis
Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel +27 more
wiley +1 more source
Fibrin Monomer in Thrombosis and Haemostasis: A Clinical Biomarker and Beyond. [PDF]
Guria K +7 more
europepmc +1 more source

