Results 201 to 210 of about 42,405 (307)

Perioperative Outcomes in Factor XI Deficiency: A Systematic Review

Haemophilia, EarlyView.
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni, Raeesah Mohammed, Silvio Ligia, Jim Douketis, Chatree Chai‐Adisaksopha, Alfonso Iorio, Davide Matino   +6 more
wiley   +1 more source

Prothrombotic Activation of Platelet Pannexin-1 Channels in Antiphospholipid Syndrome. [PDF]

Arthritis Rheumatol
de Moraes Mazetto Fonseca B, NaveenKumar SK, Yalavarthi S, Sugur K, Newman TG, Hoy CK, Sarosh C, Schaefer JK, Tambralli A, Madison JA, Zuo Y, Orsi FA, Holinstat M, Knight JS.   +13 more
europepmc   +1 more source

Management of Breakthrough Bleeding During Emicizumab Prophylaxis in Acquired Haemophilia A: Data From the GTH‐AHA‐EMI Study

Haemophilia, EarlyView.
ABSTRACT Introduction The GTH‐AHA‐EMI study showed that emicizumab reduces bleeding in patients with acquired haemophilia A (AHA). However, 22 clinically relevant new bleeds (CRNB) occurred in 14 of the 47 study patients, most of which required haemostatic treatment.
Halet Türkantoz, Christiane Dobbelstein, Richard Greil, Christina Hart, Robert Klamroth, Paul Knöbl, Johannes Oldenburg, Christian Pfrepper, Ulrich Sachs, Inga M. Schimansky, Karolin Trautmann‐Grill, Andreas Tiede   +11 more
wiley   +1 more source

Orally Administered Rhamnan Sulfate from <i>Monostroma nitidum</i> Significantly Inhibits Melanoma Metastasis in Lungs and Aorta of Mice Implanted with B16 Cells. [PDF]

Mar Drugs
Hiramoto K, Imai M, Terasawa M, Suzuki K.   +3 more
europepmc   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

Measurement of Active Thrombin Bound to Circulating D-Dimers as a Sensitive Biomarker for Prothrombotic Conditions. [PDF]

J Clin Lab Anal
Stikarova J, Chrastinova L, Svobodova K, Havlicek M, Louzil J, Ceznerova E, Hlavackova A, Pastva O, Pecherkova P, Hrachovinova I, Kucerka O, Kotlin R, Soukup P, Salaj P, Maly M, Suttnar J.   +15 more
europepmc   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Aβ₁₋₄₀ Enhances Platelet Sensitivity to Thrombin via NADPH Oxidase-ROS Signaling and Integrin α_IIbβ_₃ Engagement. [PDF]

Biomol Ther (Seoul)
Kim B, Lee BK, Kim JA, Jung YS.
europepmc   +1 more source

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source

Platelet Thrombin Receptor

Japanese Journal of Thrombosis and Hemostasis, 1993
openaire   +3 more sources