Results 61 to 70 of about 6,717 (137)

Relevance of anti‐thyroperoxidase antibodies in immune thrombocytopenia in adults: A single‐centre cohort study

British Journal of Haematology, EarlyView.
Nicolas Duhamel, Marie Ottavi, Sarah Lechtman, Nihal Martis, Charlotte Hinault‐Boyer, Julie Merindol, Pierre‐Yves Jeandel, Michael Levraut   +7 more
wiley   +1 more source

Clinical outcome, imaging and histopathological findings of liver cirrhosis in dogs

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Cirrhosis is a severe and irreversible condition resulting from chronic liver injury, characterised by extensive fibrosis and regenerative nodules. This report describes three dogs with cirrhosis. The main clinical findings included ascites, reduced body condition score and inappetence. Anaemia, thrombocytopenia, hypoalbuminaemia, and elevated
Wanderson Feliciano Duarte da Silva, Roger Fernando Neves da Silva, Edson Moleta Colodel, Pedro Eduardo Brandini Nespóli, Valeria Regia Franco Sousa   +4 more
wiley   +1 more source

The association of thrombocytopenia with haematological malignancy

British Journal of Haematology, Volume 209, Issue 2, Page 441-443, August 2026.
This review article discusses the interplay of immune dysregulation, clonality, and immunosuppressive therapies in immune thrombocytopenia and how this links to the risk of misattribution versus the development of haematological malignancy. Unresolved questions and directions for future research are also discussed. Isolated thrombocytopenia is commonly
Abi Vijenthira, Henrik Frederiksen, Michelle Sholzberg   +2 more
wiley   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, Volume 209, Issue 2, Page 420-431, August 2026.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Adenovirus vectors can infect mouse megakaryocytes – implications for vaccine-induced thrombosis/thrombocytopenia

Research and Practice in Thrombosis and Haemostasis
Background: Adenoviruses, adenoviral vector vaccines, and gene delivery systems have been implicated in thrombosis/thrombocytopenia syndrome. The underlying cause remains unknown.
Simon Collett, Linda Earnest, Melissa A. Edeling, Ashley Huey Yiing Yap, Julio Carrera Montoya, Chantal Attard, Ladina Di Rago, Alison Farley, Ashley P. Ng, Paul Monagle, Joseph Torresi   +10 more
doaj   +1 more source

P1666: EFFECT OF AGONISTS TO THROMBOPOIETIN RECEPTORS ON PLATELET GLYCOME OF PATIENTS WITH IMMUNE THROMBOCYTOPENIA

HemaSphere, 2022
E. Monzón Manzano, M. T. Alvarez Román, P. Acuña, E. G. Arias Salgado, A. Ramírez, M. Martín Salces, M. I. Rivas Pollmar, A. González Ceberino, N. V. Butta, V. Jiménez Yuste   +9 more
doaj   +1 more source

TRANSCRIPTOMIC PROFILING SUGGESTS DYSREGULATED ACTIVATION OF B AND T LYMPHOCYTES IN PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS

Hematology, Transfusion and Cell Therapy
Introduction and aims: Myeloproliferative neoplasms (MPN) are clonal hematological diseases characterized by exacerbated proliferation of cells belonging to the myeloid lineage. Gain of function driver mutations in the Janus Kinase 2 (JAK2), calreticulin
VL Bassan, RFM Felício, KCR Malmegrim, FA Castro   +3 more
doaj   +1 more source

Pragmatic Clinical Trial of Fostamatinib as Second‐Line Therapy in Adult Patients With Immune Thrombocytopenia and Insufficient Response to Prior Therapy: The Fostamatinib FORTE Trial

eJHaem, Volume 7, Issue 4, August 2026.
Amber Afzal, Robert Kribs, Sumit Sawhney, Mohit Narang, Frances Blevins, Robert Numerof, Francois Di Trapani, Sherry Ladha, Ruchika Goel   +8 more
wiley   +1 more source

Real-world use of thrombopoietic agents in treatment-naïve children with severe aplastic anemia: a multicenter retrospective study. [PDF]

Sci Rep
Chazli YE, Abdallah G, Zakaria M, Darwish A, Khalifa G, Hassan T, Elhawary E, Elbahy S, Salama M, Alrawas A, Wali Y, Zeid M.   +11 more
europepmc   +1 more source