Results 81 to 90 of about 6,730 (183)
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
Stephanie Juané Kennedy
wiley +1 more source
Introduction and aims: Myeloproliferative neoplasms (MPN) are clonal hematological diseases characterized by exacerbated proliferation of cells belonging to the myeloid lineage. Gain of function driver mutations in the Janus Kinase 2 (JAK2), calreticulin
VL Bassan +3 more
doaj +1 more source
Novel Perspectives on Thrombopoietin Receptor Agonists Applications
Abstract Second-generation thrombopoietin receptor agonists (TPO-RAs), romiplostim, eltrombopag, and avatrombopag, have been proved to be significant stimulators of megakaryopoiesis and, in the last decade, they have been incorporated in the treatment options against refractory immune thrombocytopenia in children and adults that do ...
Stafylidis, Christos +4 more
openaire +3 more sources
[Biology of thrombopoietin and its receptors].
Megakaryocytopoiesis is regulated by a number of cytokines with either stimulatory or inhibitory effects. Thrombopoietin (TPO), a cytokine with specific megakaryocyte maturational activity recently has been identified as the c-Mpl ligand. The physiological role of TPO and its potential mechanism of regulation has been investigated by generating mice ...
openaire +1 more source
Real-world use of thrombopoietic agents in treatment-naïve children with severe aplastic anemia: a multicenter retrospective study. [PDF]
Chazli YE +11 more
europepmc +1 more source
Romiplostim-N01 for cancer therapy-induced thrombocytopenia: A propensity score-matched cohort study. [PDF]
Yu T +5 more
europepmc +1 more source
MPL receptor dimerization and the thrombopoietin pathway in primary immune thrombocytopenia: from molecular mechanisms to targeted therapies. [PDF]
Wang Y +5 more
europepmc +1 more source

