Results 221 to 230 of about 62,155 (265)
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Thyroid hormone receptors and reproduction
Journal of Reproductive Immunology, 2011Thyroid disorders have a great impact on fertility in both sexes. Hyperthyroidism and hypothyroidism cause changes in sex hormone-binding globulin (SHBG), prolactin, gonadotropin-releasing hormone, and sex steroid serum levels. In females, thyroid hormones may also have a direct effect on oocytes, because it is known that specific binding sites for ...
Ralf, Dittrich +6 more
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Comprehensive Physiology, 1998
Abstract The sections in this article are: 3,5,3′ Triiodo‐ L ‐Thyronine (T 3 ) Receptors: Overview
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Abstract The sections in this article are: 3,5,3′ Triiodo‐ L ‐Thyronine (T 3 ) Receptors: Overview
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Selective Thyroid Hormone Receptor Modulators
Current Topics in Medicinal Chemistry, 2003Thyroid hormone regulates many important processes in vertebrates. Analysis of the symptoms that accompany hypo- and hyperthyroidism, the most common disorders of the thyroid, suggests that there are certain desirable biological effects brought about by an excess or deficiency of thyroid hormone, and that selective thyroid hormone receptor modulators ...
Hikari A I, Yoshihara, Thomas S, Scanlan
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Thyroid Hormone Receptors and Responses
1979Publisher Summary This chapter discusses the responses of thyroid hormone receptors. The thyroid hormone receptor is unique in that it is an intrinsic chromosomal nonhistone protein known to be involved in the regulation of the expression of specific genes. These receptors are bound to chromatin in the absence or the presence of thyroid hormone. They
J D, Baxter +11 more
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Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance
Trends in Endocrinology & Metabolism, 2005Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3). Two THR genes (A and B), located on different chromosomes, yield four T3-binding isoforms with highly conserved sequences in the DNA- and ligand-binding domains.
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The Thyroid Hormone Receptors: Molecular Basis of Thyroid Hormone Resistance
Hormone Research, 1992Major progress has been achieved in the mechanism of action of thyroid hormones thanks to the identification of the T3 receptor as the product of the proto-oncogene c-erbA. Recognition of subsets of receptors with and without T3-binding properties and of the interaction of different receptors with each other leads to new insights in cell regulation and
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