Weight Loss With GLP‐1 Agonists in Nondiabetic Adults: Systematic Review and Network Meta‐Analysis
ABSTRACT Objective Two glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) (semaglutide and liraglutide) and one dual agonist (tirzepatide) are FDA‐approved for weight loss in adults with obesity without type 2 diabetes mellitus. This systematic review and network meta‐analysis aims to compare the efficacy of these agents against each other.
Michael Lim +3 more
wiley +1 more source
Brain fatigue in Graves' disease: symptoms and presentation of a possible mechanism at the cellular level. [PDF]
Tammelin K +5 more
europepmc +1 more source
Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak +2 more
wiley +1 more source
Long-Term Thyroid Complications Post-COVID-19: A Systematic Review. [PDF]
Hommos L +13 more
europepmc +1 more source
Communication of Cost in Thyroidectomy: A Mixed‐Methods Analysis of Financial Toxicity
Abstract Objective To assess cost information provided to patients undergoing thyroidectomy. Study Design Explanatory sequential mixed‐methods study. Setting Single academic medical center. Methods Adults who underwent thyroidectomy between 1/2021 and 1/2024 completed a survey about financial toxicity.
Derek D. Kao +6 more
wiley +1 more source
Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review. [PDF]
El-Menyar A +7 more
europepmc +1 more source
The Role of Thyroidectomy in the Management of Thyroglossal Duct Carcinoma: A Systematic Review
Abstract Objective The extent of surgical management of thyroglossal duct‐associated differentiated thyroid carcinoma remains controversial. This study aims to evaluate the role of total thyroidectomy in patients with thyroglossal duct‐associated differentiated thyroid carcinoma and provide insights to support individualized, evidence‐based care.
Hidde H. IJtsma +6 more
wiley +1 more source
Another pleiotropic effect of SGLT2 inhibitors: Is it a new frontier in thyroid function regulation? [PDF]
Szklarz M +5 more
europepmc +1 more source
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu +6 more
wiley +1 more source

