Results 191 to 200 of about 2,382,295 (256)

In Silico molecular docking and molecular dynamic simulation of transferrin coated Phenytoin loaded SLNs with molecular targets of epilepsy. [PDF]

PLoS One
Zeb A, Ali H, Khan JZ, Shah FA, Alattar A, Alanazi FE.   +5 more
europepmc   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Investigating the relationship between peripheral blood transferrin receptor protein and tumor cell ferroptosis, invasion, and metastasis in bladder cancer. [PDF]

Sci Rep
Zhao L, Xu Z, Ren L, Zheng S, Gao J, Che H, Zhang A.   +6 more
europepmc   +1 more source

Examining Atopic Dermatitis Through the One Health Concept Lens

Allergy, EarlyView.
ABSTRACT This paper explores the application of the One Health framework to atopic dermatitis (AD), a complex, chronic skin disease, emphasizing interdisciplinary approaches to prevention and management. One Health integrates human, animal, environmental, and plant health, addressing challenges such as antimicrobial resistance, infectious diseases, and
Dijana Minić‐Pantić, Bernadette Abela, Jenni Lehtimäki, Alexander Zink, Erika Jensen‐Jarolim, Antonia Fettelschoss‐Gabriel, Claudia Traidl‐Hoffmann, Johannes Ring, Peter Schmid‐Grendelmeir, Pascal Prélaud, Alain Taïeb   +10 more
wiley   +1 more source

Beyond Iron: The Roles of CD71 in the Pathophysiology of Cancer-A Comprehensive Review. [PDF]

J Clin Med
Markopoulos GS, Simos YV, Tsamis KI, Gartzonika K, Peschos D, Lakkas L.   +5 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Salvianic acid A ameliorates ox-LDL-induced ferroptosis in vascular endothelial cells by regulating TFRC. [PDF]

Medicine (Baltimore)
Lu S, Yu L.
europepmc   +1 more source

Iron overload in hereditary spherocytosis: Are genetic factors the cause?

British Journal of Haematology, EarlyView.
Summary Non‐transfusional iron overload (IOL) in hereditary spherocytosis (HS) is poorly documented compared with other red blood cell disorders. We studied 13 HS adults with confirmed IOL to identify potential genetic factors. Using a next‐generation sequencing panel of 46 genes related to HS, anaemia and iron metabolism, we found no association ...
Lucie Donaty, Muriel Giansily‐Blaizot, Ivan Bertchansky, Séverine Cunat, Vincent Azoury, Perrine Mahe, Patricia Aguilar Martinez   +6 more
wiley   +1 more source

Role of Iron Metabolic Disturbances and Inflammatory Iron Biomarkers in Liver Transplant Prognosis. [PDF]

Int J Med Sci
Yu L, Xu J, Que T, Miao Z, Zhou Y, Que S, Zheng S, Liu Z.   +7 more
europepmc   +1 more source

A standard blood bank donation improves cardiometabolic health of donors: A double‐blind randomised controlled trial

British Journal of Haematology, EarlyView.
The upper panel illustrates the study design, including recruitment, randomisation, intervention and oral glucose tolerance tests (OGTTs) conducted 2 weeks before and after. The lower panel shows reductions in serum ferritin associated with lower 2‐h OGTT glucose and lower glucose area under the curve (AUC).
Diego Mora‐Gonzalez, Alfonso Moreno‐Cabañas, Lucía Gonzalez García, Ana Isabel Cobo‐Cuenca, Maria del Carmen Muñoz‐Turrillas, Ricardo Mora‐Rodriguez, Felix Morales‐Palomo   +6 more
wiley   +1 more source