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Targeted drug delivery strategies for oral cancer: the role of liposomes in drug delivery systems. [PDF]
Saberian E +8 more
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Ligand-modified multifunctional liposome-based targeted delivery platform: a multimodal cancer combination therapy strategy. [PDF]
Zhang X +15 more
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TFRC Germline Variants and Inborn Error of Immunity: Mechanistic Insights into Iron-Immune Crosstalk. [PDF]
Aljohani AH.
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Transferrin and transferrin receptors update
Free Radical Biology and Medicine, 2019In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
Hiroshi Kawabata
exaly +3 more sources
International Journal of Biochemistry and Cell Biology, 2004
With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
Philip Aisen
exaly +3 more sources
With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
Philip Aisen
exaly +3 more sources
Transferrin/transferrin receptor-mediated drug delivery
Medicinal Research Reviews, 2002AbstractSince transferrin was discovered more than half a century ago, a considerable effort has been made towards understanding tranferrināmediated iron uptake. However, it was not until recently with the identification and characterization of several new genes related to iron homeostasis, such as the hemochromatosis protein HFE and the iron ...
Zhong-Ming Qian
exaly +3 more sources
TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST
The Lancet, 1980Breast tissues from 59 patients were immunohistologically studied for transferrin and transferrin receptors. None of the 8 normal breasts or 22 benign mastopathies, and only 1 of 7 fibroadenomas were reactive for transferrin, but 16 (72.7%) of 22 carcinomas were positive and parallel sections showed histopathologically that the rective areas were ...
W P, Faulk, B L, Hsi, P J, Stevens
openaire +2 more sources
Annual Review of Medicine, 1993
The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
J D, Cook, B S, Skikne, R D, Baynes
openaire +2 more sources
The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
J D, Cook, B S, Skikne, R D, Baynes
openaire +2 more sources

