Results 201 to 210 of about 50,081 (262)

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Association between serum transferrin and overall survival in cancer patients: a multi-center cohort study. [PDF]

BMC Cancer
Zhao Q, Sun K, Wu X, Shen F, Chen X, Song C, Wang X, Xu H, Cong M, Shi H, Jia P.   +10 more
europepmc   +1 more source

Stress-Induced Dysregulation of Brain Iron Metabolism and Its Links to Neurological Disorders. [PDF]

Biology (Basel)
Dong K, Liu B, Cheng G, Li Y, Xie F, Zhang J, Qian L.   +6 more
europepmc   +1 more source

Maternal Adiposity and DNA Methylation of TfR2 and HJV Genes in Early Pregnancy: Mediating Role of Inflammation and Consequences for Iron Status. [PDF]

J Nutr
Demirdjian SP, Irwin RE, Thompson PD, Mulhern MS, Kerr MA, Ledwidge M, Rahman KL, Conway C, Rodriguez EP, McCann MT.   +9 more
europepmc   +1 more source

New insights in nanocrystal technology chemotherapeutic drugs targeting cancer with a translational research paradigm. [PDF]

Am J Transl Res
Iqbal FM, Delie F, Iqbal MO, Gul S, Kanwal S, Muzammal M, Ahmad A, Munawar N.   +7 more
europepmc   +1 more source

Specific Recognition of Glycoproteins: Design Strategies and Application Prospects of Molecularly Imprinted Polymers. [PDF]

Int J Mol Sci
Xie P, Chen ZY, Xie CF, Fan JP.
europepmc   +1 more source

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Transferrin receptor 1

International Journal of Biochemistry and Cell Biology, 2004
With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
Philip Aisen
exaly   +3 more sources

Transferrin and transferrin receptors update

Free Radical Biology and Medicine, 2019
In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
Hiroshi Kawabata
exaly   +3 more sources

Transferrin/transferrin receptor-mediated drug delivery

Medicinal Research Reviews, 2002
AbstractSince transferrin was discovered more than half a century ago, a considerable effort has been made towards understanding tranferrin‐mediated iron uptake. However, it was not until recently with the identification and characterization of several new genes related to iron homeostasis, such as the hemochromatosis protein HFE and the iron ...
Zhong Ming Qian
exaly   +3 more sources