Results 1 to 10 of about 133,411 (307)

<i>Mallotus japonicus</i> extract suppresses ferroptosis by inhibiting transferrin receptor-mediated ferrous ion uptake in human tubular epithelial HK2 cells. [PDF]

J Clin Biochem Nutr
Kamiya T, Nishimura M, Otsuka T, Yoshinaka H, Maruyama H, Kono H, Hara H.   +6 more
europepmc   +1 more source

Soluble transferrin receptor is associated with red blood cell transfusion in infant cardiac surgery. [PDF]

Transl Pediatr
Gao P, Liu J, Wang H, Wang W, Jin Y, Zhang P, Liu J.   +6 more
europepmc   +1 more source

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization. [PDF]

Nat Commun
Zhang R, Shen Y, Zhou X, Li J, Zhao H, Zhang Z, Zhao J, Jin H, Guo S, Ding H, Nie G, Zhang Z, Wang Y, Yan X, Fan K.   +14 more
europepmc   +1 more source

Transferrin/transferrin receptor‐mediated drug delivery

Medicinal Research Reviews, 2002
AbstractSince transferrin was discovered more than half a century ago, a considerable effort has been made towards understanding tranferrin‐mediated iron uptake. However, it was not until recently with the identification and characterization of several new genes related to iron homeostasis, such as the hemochromatosis protein HFE and the iron ...
Hongyan, Li, Zhong Ming, Qian
openaire   +4 more sources

Serum Transferrin Receptor

Annual Review of Medicine, 1993
The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
J D, Cook, B S, Skikne, R D, Baynes
openaire   +3 more sources

Transferrin and transferrin receptors update

Free Radical Biology and Medicine, 2019
In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
openaire   +2 more sources

Transferrin receptor 1

The International Journal of Biochemistry & Cell Biology, 2004
With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
openaire   +2 more sources

Reticulocyte membrane transferrin receptors

Canadian Journal of Biochemistry, 1980
A membrane protein with specific transferrin binding activity has been isolated from rabbit reticulocytes. The isolation procedure involved the immunoprecipitation by antibody to transferrin of transferring–receptor complexes from reticulocyte membrane proteins which had been solubilized with nonionic detergent.
B, Ecarot-Charrier, V L, Grey, A, Wilczynska, H M, Schulman   +3 more
openaire   +2 more sources

Serum transferrin receptor

American Journal of Hematology, 2008
AbstractTransferrin receptors (TfRs) are the conventional pathway by which cells acquire iron for physiological requirements. Under iron‐deficient conditions there is an increased concentration of surface TfR, especially on bone marrow erythroid precursors, as a mechanism to sequester needed iron.
openaire   +2 more sources

Erythropoiesis and transferrin receptors

Current Opinion in Hematology, 2015
The type 1 transferrin receptor (TfR1) is well known as a key player in erythroid differentiation through its role in iron uptake. Recently, it has been demonstrated that TfR1 could also have signaling functions in erythroid cells. Moreover, the second transferrin receptor, TfR2, whose signaling functions in hepatic cells are well established, was ...
Ivan C, Moura, Olivier, Hermine, Catherine, Lacombe, Patrick, Mayeux   +3 more
openaire   +2 more sources