Results 41 to 50 of about 81,753 (161)

Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis

Research
Immune recognition and activation by the peptide-laden major histocompatibility complex–T cell receptor (TCR)–CD3 complex is essential for anti-tumor immunity. Tumors may escape immune surveillance by dissembling the complex.
Ruomei Cheng, Xiaopeng Tang, Qiyu Zhao, Yuming Wang, Wenlin Chen, Gan Wang, Chenxi Wang, James Mwangi, Qiumin Lu, Dawit Adisu Tadese, Xudong Zhao, Caiwen Ou, Ren Lai   +12 more
doaj   +1 more source

Interrelation of the content of transferrin, erythrocytes with the functional activity of leukocytes of peripheral venous blood in residents of the European North of the Russian Federation

Якутский медицинский журнал
The relationship between the content of transferrin and erythrocytes and the functional activity of leukocytes of peripheral venous blood in residents of the European North of the Russian Federation have been studied.
K. O. Pashinskaya, A. V. Samodova, L. K. Dobrodeyeva   +2 more
doaj   +1 more source

The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia

Eurasian Journal of Medicine, 2019
Objective: Iron deficiency anemia is the most common cause of microcytic anemia throughout the world. Ferritin levels are good indicators of iron stores; however, levels may increase irrespective of iron stores in cases of chronic disease.
Osman Yokus, Bilal Yilmaz, Murat Albayrak, Ozlem Sahin Balcik, Mehmet Rami Helvaci, Engin Sennaroglu   +5 more
doaj   +1 more source

Transferrin Receptor Is a Specific Ferroptosis Marker

Cell Reports, 2020
Summary: Ferroptosis is a type of regulated cell death driven by the iron-dependent accumulation of oxidized polyunsaturated fatty acid-containing phospholipids.
Huizhong Feng, Kenji Schorpp, Jenny Jin, Carrie E. Yozwiak, Benjamin G. Hoffstrom, Aubrianna M. Decker, Presha Rajbhandari, Michael E. Stokes, Hannah G. Bender, Joleen M. Csuka, Pavan S. Upadhyayula, Peter Canoll, Koji Uchida, Rajesh K. Soni, Kamyar Hadian, Brent R. Stockwell   +15 more
doaj   +1 more source

Serum transferrin receptor in polycythemia

Haematologica, 1998
We measured serum transferrin receptor (sTfR) levels in 22 patients with polycythemia vera and in 26 cases of secondary polycythemia. In our study, raised sTfR levels in both polycythemia groups were related to iron deficiency.
R Manteiga, AF Remacha, MP Sarda, J Ubeda   +3 more
doaj  

Characterization of Tfrc-mutant mice with microcytic phenotypes

Blood Advances, 2018
: To identify novel regulators of erythropoiesis, we performed independent forward genetic screens using the chemical mutagen ENU in mice. Among progeny displaying microcytic red-cell phenotypes, 7 independent mouse strains harboring mutations within the
Ashlee J. Conway, Fiona C. Brown, Gerhard Rank, Benjamin T. Kile, Craig J. Morton, Stephen M. Jane, David J. Curtis   +6 more
doaj   +1 more source

Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors

Haematologica, 2011
Background Currently used indicators of iron status have limitations. Hepcidin, a key regulator of iron metabolism, is reduced in iron deficiency. We sought to determine the properties of hepcidin as a diagnostic test of iron deficiency.Design and ...
Sant-Rayn Pasricha, Zoe McQuilten, Mark Westerman, Anthony Keller, Elizabeta Nemeth, Tomas Ganz, Erica Wood   +6 more
doaj   +1 more source

Transferrin Receptor Mediated Brain Uptake During Ischemia and Reperfusion

Journal of Pharmacy & Pharmaceutical Sciences, 2013
Purpose. Drug delivery by transferrin receptor-mediated transport at the blood-brain barrier has shown beneficial effects in animal models of stroke, but it is unclear whether receptor mediated uptake remains functional in the ischemic tissue.
Jiukuan Hao, Ulrich Bickel
doaj   +1 more source

The significance of soluble transferrin receptors in diagnosing iron deficiency anemia

Romanian Journal of Laboratory Medicine, 2015
Introduction. In recent years, determination of soluble transferrin receptor levels has been emerging as a test that can reliably indicate iron deficiency in various states, and that is non-invasive and easy to use.
Tijanić Ivan, Vučić Miodrag, Mačukanović Golubović Lana   +2 more
doaj   +1 more source

Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3'UTR.

PLoS ONE, 2018
The bloodstream form of the parasite Trypanosoma brucei obtains iron from its mammalian host by receptor-mediated endocytosis of host transferrin through its own unique transferrin receptor (TbTfR).
Corinna Benz, Winston Lo, Nadin Fathallah, Ashley Connor-Guscott, Henry J Benns, Michael D Urbaniak   +5 more
doaj   +1 more source