Ferroptosis in Pneumoconiosis: From Molecular and Cellular Mechanisms to Therapeutic Strategies
Targeting lung various cells to alleviate pneumoconiosis by suppressing ferroptosis. AAV9‐HGF, adeno‐associated virus‐hepatocyte growth factor; DFP, deferiprone; DHQ, dihydroquercetin; Fer‐1, ferrostatin‐1; IL‐1β, interleukin‐1β; NMN, nicotinamide mononucleotide; sh‐SLC39A14, shRNA targeting solute carrier family 39 member 14; si‐OC‐STAMP, siRNA ...
Mengli Yan+4 more
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Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent manner. [PDF]
Qian X+31 more
europepmc +1 more source
Polyethylene glycol‐functionalized graphene oxide (PEG‐GO) nanocomposites revolutionize nanomedicine with their high surface area and tunable properties. This review explores their synthesis, characterization, and applications in drug delivery, gene therapy, biosensing, and photothermal therapy.
Oluwasegun Chijioke Adekoya+4 more
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RAB23 facilitates clathrin-coated nascent vesicle formation at the plasma membrane and modulates cell signaling. [PDF]
Hasan MR+5 more
europepmc +1 more source
Abstract Micronutrient uptake is impaired after pancreatico‐duodenectomy (PD) because of malabsorption, reduced absorptive capacity, and poor oral intake. Biochemical depletion is reported in cohort studies, but deficiency states are predominantly reported in case reports, making it difficult to assess occurrence rates.
Mary E. Phillips+3 more
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Effect of erythropoiesis-stimulating agent types on malignancy in hemodialysis patients. [PDF]
Kang SH, Lim YJ, Kim BY, Choi JY, Do JY.
europepmc +1 more source
Phytochemical Nanoparticles for the Treatment of Neurological Disorders
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
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Iron-dependent mechanisms in <i>Acinetobacter baumannii</i>: pathogenicity and resistance. [PDF]
Zhang R+5 more
europepmc +1 more source
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen+7 more
wiley +1 more source
Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer. [PDF]
Bolesławska I+4 more
europepmc +1 more source