Results 41 to 50 of about 416,152 (310)
Tumor necrosis factor antagonists: structure, function and tuberculosis risks [PDF]
Einstein (São Paulo), 2009 New therapeutic options bring new problems and also new knowledge about disease mechanisms. Ten years ago the first antagonist to tumor necrosis factor was first used to treat inflammatory diseases and the use of anti-cytokines has proved to be a ...
Jacyr Pasternak
doaj
Analytical Cellular Pathology, 2010 Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) initiates apoptosis in tumor cells upon binding to its cognate agonistic receptors, death receptors 4 and 5 (DR4 and DR5). The activity of the insulin-like growth factor 1 (IGF-1)
Bodvael Pennarun +5 more
doaj +1 more source
Enhancement of experimental metastasis by tumor necrosis factor [PDF]
, 1993 The influence of endogenous and exogenous tumor necrosis factor (TNF) on metastasis was investigated in an experimental fibrosarcoma metastasis model.
Echtenacher, Bernd +5 more
core +2 more sources
Molecular Pain, 2016 Despite mu opioid receptor agonists are the cornerstones of moderate-to-severe acute pain treatment, their effectiveness in chronic pain conditions is controversial.
Nunzio Vicario PhD (cand) +6 more
doaj +1 more source
The role of the TNF receptors and apoptosis inducing ligands in tumor growth [PDF]
The Ukrainian Biochemical Journal, 2016 Tumor necrosis factor (TNF) superfamily receptors and TNF apoptosis inducing ligands play an important role in the realization of TNF function and control tumor growth.
O. H. Minchenko1 +3 more
doaj +1 more source
Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected B cell lines. [PDF]
, 1993 Because human lymphotoxin (LT) was originally isolated from a lymphoblastoid cell line, we investigated the role of this molecule in three newly established Epstein-Barr virus (EBV)-infected human B cell lines.
Aggarwal, BB +8 more
core +1 more source
Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
, 2014 Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Frontiers in MicrobiologyIntroductionThe proteolytic activity of A Disintegrin and Metalloproteinase 17 (ADAM17) regulates the release of tumor necrosis factor (TNF) and TNF receptors (TNFRs) from cell surfaces.
José Alberto Choreño-Parra +30 more
doaj +1 more source
Nail Lichen Planus: Successful Treatment with Etanercept
Case Reports in Dermatology, 2010 Background: Etanercept is a fully human tumor necrosis factor α receptor fusion protein that binds tumor necrosis factor α with greater affinity than natural receptors.
N. Irla +3 more
doaj +1 more source