Results 21 to 30 of about 256,756 (267)

TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitro. [PDF]

PLoS ONE, 2011
Signaling by Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) and Fas ligand (FasL) has been proposed to contribute to the chemosensitivity of tumor cells treated with various other anti-cancer agents.
Christina Menke, Tatiana Goncharov, Lubna Qamar, Christopher Korch, Heide L Ford, Kian Behbakht, Andrew Thorburn   +6 more
doaj   +1 more source

Relationship between Dynamics of TNF-α and Its Soluble Receptors in Saliva and Periodontal Health State

Dentistry Journal, 2022
Soluble tumor necrosis factor receptors 1 and 2 (sTNF-R1 and sTNF-R2) are reported to protect against excessive TNF-α, a primary mediator of systemic responses to infection.
Ryota Kibune, Kosuke Muraoka, Masaki Morishita, Wataru Ariyoshi, Shuji Awano   +4 more
doaj   +1 more source

Regulation of Tumor Necrosis Factor Receptors on Phagocytes

Experimental Biology and Medicine, 1992
Tumor necrosis factor (TNF)-α is a cytokine secreted by monocytes, macrophages, T cells, natural killer cells, mast cells, and neutrophils (PMN) in response to stimulation in vitro with lipopolysaccharide (LPS), viruses, antigens, and during infection, allograft rejection or injury (1–4).
A H, Ding, F, Porteu
openaire   +2 more sources

The rs11684747 and rs55790676 SNPs of ADAM17 influence tuberculosis susceptibility and plasma levels of TNF, TNFR1, and TNFR2

Frontiers in Microbiology
IntroductionThe proteolytic activity of A Disintegrin and Metalloproteinase 17 (ADAM17) regulates the release of tumor necrosis factor (TNF) and TNF receptors (TNFRs) from cell surfaces.
José Alberto Choreño-Parra, José Alberto Choreño-Parra, Lucero A. Ramon-Luing, Manuel Castillejos, Emmanuel Ortega-Martínez, Emmanuel Ortega-Martínez, Emmanuel Ortega-Martínez, Alan Rodrigo Tapia-García, Alan Rodrigo Tapia-García, Melvin Barish Matías-Martínez, Melvin Barish Matías-Martínez, Alfredo Cruz-Lagunas, Gustavo Ramírez-Martínez, Itzel Alejandra Gómez-García, Itzel Alejandra Gómez-García, Jazmín Ariadna Ramírez-Noyola, Jazmín Ariadna Ramírez-Noyola, Beatriz Garcia-Padrón, Beatriz Garcia-Padrón, Karen Gabriel López-Salinas, Karen Gabriel López-Salinas, Fabiola Jiménez-Juárez, Fabiola Jiménez-Juárez, Parménides Guadarrama-Ortiz, Citlaltepetl Salinas-Lara, Citlaltepetl Salinas-Lara, Karolina Bozena-Piekarska, Marcela Muñóz-Torrico, Leslie Chávez-Galán, Joaquín Zúñiga, Joaquín Zúñiga   +30 more
doaj   +1 more source

Inhibition of IGF-1R-Dependent PI3K Activation Sensitizes Colon Cancer Cells Specifically to DR5-Mediated Apoptosis But Not to rhTRAIL

Analytical Cellular Pathology, 2010
Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) initiates apoptosis in tumor cells upon binding to its cognate agonistic receptors, death receptors 4 and 5 (DR4 and DR5). The activity of the insulin-like growth factor 1 (IGF-1)
Bodvael Pennarun, Jan H. Kleibeuker, Tjitske Oenema, Janet H. Stegehuis, Elisabeth G.E. de Vries, Steven de Jong   +5 more
doaj   +1 more source

Intrinsic cardiac adrenergic cells contribute to LPS-induced myocardial dysfunction

Communications Biology, 2022
Yang et al report that intrinsic cardiac adrenergic cell-derived norepinephrine promotes myocardial dysfunction in response to LPS. They demonstrate norepinephrine produced by these cells activated β1-adrenergic receptors on cardiomyocytes increasing the
Duomeng Yang, Xiaomeng Dai, Yun Xing, Xiangxu Tang, Guang Yang, Andrew G. Harrison, Jason Cahoon, Hongmei Li, Xiuxiu Lv, Xiaohui Yu, Penghua Wang, Huadong Wang   +11 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Tumor necrosis factor antagonists: structure, function and tuberculosis risks [PDF]

Einstein (São Paulo), 2009
New therapeutic options bring new problems and also new knowledge about disease mechanisms. Ten years ago the first antagonist to tumor necrosis factor was first used to treat inflammatory diseases and the use of anti-cytokines has proved to be a ...
Jacyr Pasternak
doaj  

Repeated activation of delta opioid receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain

Molecular Pain, 2016
Despite mu opioid receptor agonists are the cornerstones of moderate-to-severe acute pain treatment, their effectiveness in chronic pain conditions is controversial.
Nunzio Vicario PhD (cand), Rosalba Parenti PhD, Giuseppina Aricò PhD, Rita Turnaturi PhD, Giovanna Maria Scoto MS, Santina Chiechio PhD, Carmela Parenti PhD   +6 more
doaj   +1 more source

The role of the TNF receptors and apoptosis inducing ligands in tumor growth [PDF]

The Ukrainian Biochemical Journal, 2016
Tumor necrosis factor (TNF) superfamily receptors and TNF apoptosis inducing ligands play an important role in the realization of TNF function and control tumor growth.
O. H. Minchenko1, D. O. Tsymbal1, D. O. Minchenko1,2,, О. O. Ratushna1   +3 more
doaj   +1 more source