Results 11 to 20 of about 256,662 (267)
Tumor necrosis factor-alpha and its receptors in epithelial ovarian cancer.
The aim of the present study was to characterize the expression pattern of tumor necrosis factor (TNF)-alpha and its receptors (TNF-Rs) in the epithelial ovarian cancer (EOC) and compare these results with the outcome of 126 patients.
Jacek Nikliński +7 more
doaj +1 more source
Tumor necrosis factor receptor cross‐talk [PDF]
Extensive research has been performed to unravel the mechanistic signaling pathways mediated by tumor necrosis factor receptor 1 (TNFR1), by contrast there is limited knowledge on cellular signaling upon activation of TNFR2. Recently published data have revealed that these two receptors not only function independently, but also can influence each other
Petrus J W, Naudé +3 more
openaire +2 more sources
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
doaj +1 more source
Pathogens and Dead Cells Cooperate with Cytokines in Activating the Innate and Adaptive Response
After microbial invasion and tissue damage, a set of cytokines, including interleukin-1α (IL-1α), IL-1β, IL-6, IL-18 and tumor necrosis factor-α (TNF-α), and microbial and endogenous molecules named pathogen-associated molecular pattern (PAMPs) and ...
J.E. Belizário
doaj +1 more source
Tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) are a family of structurally related proteins that transduces signals from members of TNFR superfamily and various other immune receptors.
Jian-Hong Shi, Shao-Cong Sun
doaj +1 more source
Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice. [PDF]
Tumor necrosis factor-α (TNF-α) is a key factor for the pathogenesis of inflammatory bowel diseases (IBD), whose function is known to be mediated by TNF receptor 1 (TNFR1) or 2.
Ke Wang +13 more
doaj +1 more source
Mechanisms of cell death in acute liver failure
Acute liver failure (ALF) occurs when the extent of hepatocyte death exceeds the regenerative capacity of the liver. The mode of liver cell death that is predominantly induced in ALF, i.e.
Heike eBantel
doaj +1 more source
Regulation of Tumor Necrosis Factor Receptors on Phagocytes
Tumor necrosis factor (TNF)-α is a cytokine secreted by monocytes, macrophages, T cells, natural killer cells, mast cells, and neutrophils (PMN) in response to stimulation in vitro with lipopolysaccharide (LPS), viruses, antigens, and during infection, allograft rejection or injury (1–4).
A H, Ding, F, Porteu
openaire +2 more sources
Characterization of Chicken Tumor Necrosis Factor-α, a Long Missed Cytokine in Birds
Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine playing critical roles in host defense and acute and chronic inflammation. It has been described in fish, amphibians, and mammals but was considered to be absent in the avian genomes.
Franziska Rohde +8 more
doaj +1 more source
BackgroundAlthough hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of tumor necrosis factor (TNF)-related biomarkers in reflecting the prognosis.
Tomohito Gohda +6 more
doaj +2 more sources

