Results 11 to 20 of about 256,756 (267)
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Indian Journal of Ophthalmology, 2012 Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
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Tumor necrosis factor: receptors on hematopoietic cells [PDF]
Blood, 1987 Tumor necrosis factor (TNF) is a monokine that is cytotoxic/cytostatic for a variety of tumor cells and has multiple effects on normal cells. We demonstrate that normal and malignant human myeloid cells express a single class of high-affinity receptors (400 to 1,900 per cell, KD 20 to 90 pmol/L) for TNF.
R, Munker, J, DiPersio, H P, Koeffler
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Pathogens and Dead Cells Cooperate with Cytokines in Activating the Innate and Adaptive Response
European Journal of Inflammation, 2011 After microbial invasion and tissue damage, a set of cytokines, including interleukin-1α (IL-1α), IL-1β, IL-6, IL-18 and tumor necrosis factor-α (TNF-α), and microbial and endogenous molecules named pathogen-associated molecular pattern (PAMPs) and ...
J.E. Belizário
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Frontiers in Immunology, 2018 Tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) are a family of structurally related proteins that transduces signals from members of TNFR superfamily and various other immune receptors.
Jian-Hong Shi, Shao-Cong Sun
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Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice. [PDF]
PLoS ONE, 2012 Tumor necrosis factor-α (TNF-α) is a key factor for the pathogenesis of inflammatory bowel diseases (IBD), whose function is known to be mediated by TNF receptor 1 (TNFR1) or 2.
Ke Wang +13 more
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Mechanisms of cell death in acute liver failure
Frontiers in Physiology, 2012 Acute liver failure (ALF) occurs when the extent of hepatocyte death exceeds the regenerative capacity of the liver. The mode of liver cell death that is predominantly induced in ALF, i.e.
Heike eBantel
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Characterization of Chicken Tumor Necrosis Factor-α, a Long Missed Cytokine in Birds
Frontiers in Immunology, 2018 Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine playing critical roles in host defense and acute and chronic inflammation. It has been described in fish, amphibians, and mammals but was considered to be absent in the avian genomes.
Franziska Rohde +8 more
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Tumor necrosis factor receptor cross‐talk [PDF]
The FEBS Journal, 2011 Extensive research has been performed to unravel the mechanistic signaling pathways mediated by tumor necrosis factor receptor 1 (TNFR1), by contrast there is limited knowledge on cellular signaling upon activation of TNFR2. Recently published data have revealed that these two receptors not only function independently, but also can influence each other
Petrus J W, Naudé +3 more
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PLoS ONE, 2022 BackgroundAlthough hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of tumor necrosis factor (TNF)-related biomarkers in reflecting the prognosis.
Tomohito Gohda +6 more
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Arquivos Brasileiros de Cardiologia, 2001 OBJECTIVE: The association between cytokines and troponin-I with cardiac function after cardiac surgery with cardiopulmonary bypass remains a topic of continued investigation.
Neverton Savaris +2 more
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