Results 151 to 160 of about 670,193 (365)

The role of VEGF receptors in angiogenesis; complex partnerships [PDF]

, 2018
.: Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis but also have profound effects on neural cells. VEGFs are predominantly produced by endothelial, hematopoietic and stromal cells in response to
Ballmer-Hofer, K., Cébe-Suarez, S., Zehnder-Fjällman, A.   +2 more
core  

Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition [PDF]

, 2017
No abstract ...
Danser, A.H. Jan, Herrmann, Joerg, Lang, Ninian N., Touyz, Rhian M., van den Meiracker, Anton H.   +4 more
core   +1 more source

Development of a Computationally Optimized Model of Cancer-induced Angiogenesis through Specialized Cellular Mechanics [PDF]

arXiv, 2016
Angiogenesis, the development of new vasculature, is a critical process in the growth of new tumors. Driven by a goal to understand this aspect of cancer proliferation, I develop a discrete computationally optimized mathematical model of angiogenesis that specializes in intercellular interactions.
arxiv  

Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells.

Blood, 2009
Expression of vascular endothelial growth factor (VEGF) is tightly regulated to achieve normal angiogenesis. The objective was to examine regulation of VEGF by the activin-like kinase receptors (ALKs) ALK1 and ALK5.
Esther S Shao, Laura Lin, Yucheng Yao, K. Boström   +3 more
semanticscholar   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Vascular endothelial growth factor acts as an osteolytic factor in breast cancer metastases to bone [PDF]

Vascular endothelial growth factor (VEGF) is a proangiogenic cytokine that is expressed highly in many solid tumours often correlating with a poor prognosis.
A Boyum, A Boyum, A Sawano, B Barleon, B Fernandez Pujol, C Minkin, H Yasuda, I Itonaga, J Faust, J Folkman, J R Williams, JD Jong, JD Jong, K Henriksen, K Matsuzaki, M A Birch, M Clauss, M Kaku, M Nakagawa, N Akeno, N Ortega, O Peyruchaud, R Coleman, S E Aldridge, S Niida, S Wei, SH Allen, SM Hsu, SM Hsu, T Guise, T Veikkola, T W J Lennard, V Shalhoub, Y Matsumoto   +33 more
core   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

A Spatial Model of Tumor-Host Interaction: Application of Chemotherapy [PDF]

Math. Biosci. Eng. 6(3):521-545, 2009, 2008
In this paper we consider chemotherapy in a spatial model of tumor growth. The model, which is of reaction-diffusion type, takes into account the complex interactions between the tumor and surrounding stromal cells by including densities of endothelial cells and the extra-cellular matrix.
arxiv  

Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications

Biomedicines
Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease (CKD) and end-stage renal disease worldwide, affecting approximately 40% of individuals with type 2 diabetes (T2DM) and 30% of those with type 1 diabetes (T1DM). As the prevalence
Lyubomir Gaydarski, Kristina Petrova, Ivan Angushev, Stancho Stanchev, Alexandar Iliev, Nikola Stamenov, Vidin Kirkov, Boycho Landzhov   +7 more
doaj   +1 more source

Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]

, 2013
Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Plate, Karl H., Schneider, Fabian T., Wittko-Schneider, Ina M.   +2 more
core   +1 more source