Results 141 to 150 of about 10,420,356 (335)

Sphingosine-1-phosphate affects myocardial vascular homeostasis by regulating the balance of sphingosine-1-phosphate receptors in the hearts of diabetic mice

open access: yesJournal of International Medical Research
Objective This study aimed to explore the effect of sphingosine-1-phosphate on vascular homeostasis in the myocardium of diabetic mice. Methods Bioinformatics analyses were performed to analyze the targets and function of sphingosine-1-phosphate in ...
Guozhu Jin   +4 more
doaj   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

open access: yesAdvanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn   +5 more
wiley   +1 more source

Gene Expression Analysis of VEGF and Its Receptors and Assessment of Its Serum Level in Unexplained Recurrent Spontaneous Abortion [PDF]

open access: yesCell Journal, 2015
Objective: Unexplained recurrent spontaneous abortion (URSA) is one of the main complications of pregnancy which is usually defined as three or more consecutive pregnancy losses before the 20th week of gestation without a known cause.
Elham Amirchaghmaghi   +5 more
doaj  

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

open access: yesAdvanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti   +4 more
wiley   +1 more source

Placenta growth factor not vascular endothelial growth factor A or C can predict the early recurrence after radical resection of hepatocellular carcinoma

open access: yes, 2009
The purpose of this study was to evaluate the relationship between the expression of PlGF in tumor tissue and clinical outcomes in HCC patients. Tumor PlGF and vascular endothelial growth factor (VEGF)-A and VEGF-C mRNA were analyzed.
何明志;陳炯年;李心予;謝豐舟;孫家棟;章齊倫;賴允婷;李伯皇   +1 more
core   +1 more source

Extrusion‐Based Bioprinting of Living Bioinks for Tissue and Organ Engineering

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting is presented as the most versatile route for fabricating living, heterogeneous tissues. Its ability to combine diverse bioinks, support matrices, and advanced printhead geometries transforms familiar constraints into powerful biofabrication opportunities.
Eric Silberman   +4 more
wiley   +1 more source

Endothelial injury and repair in vasculitis of the young [PDF]

open access: yes, 2009
The vasculitides are a wide spectrum of disorders which are characterised by vascular inflammation. Endothelial injury can occur as a consequence of inappropriate inflammation and is central to the pathogenesis of these varied diseases.
Clarke, L.
core  

Ibuprofen and indomethacin differentially regulate vascular endothelial growth factor and its receptors in ductus arteriosus endothelial cells

open access: yes, 2017
BackgroundCyclooxygenase inhibitors are widely applied to facilitate ductal closure in preterm infants. The mechanisms that lead to patent ductus arteriosus closure are incompletely understood.
Sandra Akanbi   +5 more
core   +1 more source

Clinical utility of ramucirumab in advanced gastric cancer

open access: yesBiologics: Targets & Therapy, 2015
Matthew MK Chan,1,2 Katrin M Sjoquist,1,3 John R Zalcberg4 1NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia; 2Department of Medical Oncology, Central Coast Cancer Centre, Gosford Hospital, Gosford, NSW, Australia; 3Cancer Care ...
Chan MMK, Sjoquist KM, Zalcberg JR
doaj  

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

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