Results 1 to 10 of about 26,981 (164)
Biomedicines, 2021 Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for adapting to terrestrial environments.
Samantha Sparapani +72 more
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Frontiers in Pharmacology, 2023 The vasopressin/oxytocin signaling system is present in both protostomes and deuterostomes and plays various physiological roles. Although there were reports for both vasopressin-like peptides and receptors in mollusc Lymnaea and Octopus, no precursor or
Ju-Ping Xu +15 more
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The Journal of Headache and Pain, 2022 Background Hypothalamus is a key region in migraine attacks. In addition, women are disproportionately affected by migraine. The calcitonin gene-related peptide (CGRP) system is an important key player in migraine pathophysiology. CGRP signaling could be
Aida Maddahi +2 more
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Gastroenterology Insights, 2023 Hepatorenal syndrome stands as one of several potential triggers of acute kidney injury in individuals grappling with either acute or persistent liver ailments. The nature of the decline in kidney function has led to the identification of two variants of
Ahlam Ayyad, Rami A. Al-Horani
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Vasopressin receptor antagonists [PDF]
Kidney International, 2006 The first non-peptide vasopressin receptor antagonist (VRA) was recently approved by the United States Food and Drug Administration, and several others are now in late stages of clinical development. Phase 3 trials indicate that these agents predictably reduce urine osmolality, increase electrolyte-free water excretion, and raise serum sodium ...
Greenberg, A., Verbalis, J.G.
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Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]
, 2013 Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P +4 more
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A case of pheochromocytoma crisis with persistent hypotension successfully managed with vasopressin
Urology Case Reports, 2021 We report the first case of pheochromocytoma crisis with hypotension that was successfully treated with vasopressin. A 64-year-old patient was diagnosed as pheochromocytoma crisis.
Daigo Chiba +3 more
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Current Research in Physiology, 2022 The mechanisms involved in urinary bladder control are not fully understood, but it is well accepted that a complex central network is involved in micturition control.
Luciana S.S. Neri +6 more
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Vasopressin and its analogues in shock states: a review
Annals of Intensive Care, 2020 Activation of arginine–vasopressin is one of the hormonal responses to face vasodilation-related hypotension. Released from the post-pituitary gland, vasopressin induces vasoconstriction through the activation of V1a receptors located on vascular smooth ...
Julien Demiselle +3 more
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Vasopressin V2 receptor antagonists [PDF]
Cardiovascular Research, 2001 Hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and disorders of water retention such as congestive heart failure and cirrhosis is a common problem encountered in the care of the medical patient. Thus far, available treatment modalities for disorders of excess arginine vasopressin (AVP) secretion or action have ...
L L, Wong, J G, Verbalis
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