Results 91 to 100 of about 50,162 (238)

Words to live by: Using medic impressions to identify the need for prehospital lifesaving interventions

Academic Emergency Medicine, Volume 32, Issue 5, Page 516-525, May 2025.
Abstract Background Prehospital emergencies require providers to rapidly identify patients’ medical condition and determine treatment needs. We tested whether medics’ initial, written impressions of patient condition contain information that can help identify patients who require prehospital lifesaving interventions (LSI) prior to or during transport ...
Aaron C. Weidman, Zach Sedor‐Schiffhauer, Chase Zikmund, David D. Salcido, Francis X. Guyette, Leonard S. Weiss, Ronald K. Poropatich, Michael R. Pinsky   +7 more
wiley   +1 more source

Hormones and nocturia : guidelines for medical treatment? [PDF]

, 2014
Everaert, Karel, Goessaert, An-Sofie, Kapila, Ayush, Vande Walle, Johan   +3 more
core   +1 more source

Altered activity within the social behavior neural network in adolescent rats following prenatal alcohol exposure and/or early‐life adversity

Alcohol, Clinical and Experimental Research, EarlyView.
Prenatal alcohol exposure (PAE) and early‐life adversity (ELA) independently and interactively disrupted neural activity within the social behavior network in adolescent rats, with age‐ and sex‐specific effects. PAE primarily dampened amygdala activity, while ELA altered medial prefrontal cortex responses. These findings reveal how different early‐life
Parker J. Holman, Linda Ellis, Amanda Chao, Cecilia Mitchell, Charlis Raineki, Joanne Weinberg   +5 more
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

Andrology, EarlyView.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante, Clara Lazzaretti, Ali Ahmad, Massimiliano Colzani, Filippo Vignali, Michele Zoli, Manuela Simoni   +6 more
wiley   +1 more source

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

PROTEOMICS, EarlyView.
Paul Perco, Matthias Ley, Kinga Kęska‐Izworska, Dorota Wojenska, Enrico Bono, Samuel M. Walter, Lucas Fillinger, Klaus Kratochwill   +7 more
wiley   +1 more source

Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review

Artificial Organs, EarlyView.
High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta, Jacopo D’Andria Ursoleo, Alice Bottussi, Samuele Bugo, Fabrizio Monaco   +4 more
wiley   +1 more source

Fluid intake and recurrence and progression risk of patients with non‐muscle‐invasive bladder cancer

BJU International, EarlyView.
Objectives To evaluate the association of pre‐ and post‐diagnosis fluid intake with non‐muscle‐invasive bladder cancer (NMIBC) recurrence and progression risk. Patients and Methods Data were used from the multicentre prospective cohort study UroLife.
Ivy Beeren, Hilde Meijer, Antoine G. van der Heijden, Katja K.H. Aben, J. Alfred Witjes, Lambertus A.L.M. Kiemeney, Alina Vrieling   +6 more
wiley   +1 more source

Microscopy and spectroscopy approaches to study GPCR structure and function

British Journal of Pharmacology, EarlyView.
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl, Maria Majellaro, Alexey Bondar   +2 more
wiley   +1 more source

Arrestin‐centred interactions at the membrane and their conformational determinants

British Journal of Pharmacology, EarlyView.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals   +3 more
wiley   +1 more source