Results 111 to 120 of about 50,162 (238)

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

open access: yesCell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang   +8 more
wiley   +1 more source

Hemodynamic and ADH responses to central blood volume shifts in cardiac-denervated humans [PDF]

open access: yes
Hemodynamic responses and antidiuretic hormone (ADH) were measured during body position changes designed to induce blood volume shifts in ten cardiac transplant recipients to assess the contribution of cardiac and vascular volume receptors in the control
Benjamin, B. A.   +8 more
core   +1 more source

Developments in albuminuria testing: A key biomarker for detection, prognosis and surveillance of kidney and cardiovascular disease—A practical update for clinicians

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Albuminuria, the abnormal presence of albumin in urine, is a key marker of kidney damage and a strong predictor of kidney and cardiovascular outcomes. Its clinical significance has evolved from early historical observations to its current role in chronic kidney disease (CKD) detection, risk stratification and treatment monitoring.
Jelle M. Beernink   +4 more
wiley   +1 more source

A review of the safety of sodium‐glucose co‐transporter‐2 inhibitors

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract The development of sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors represents a major turning point in the effort to preserve kidney function and prevent cardiovascular events and heart failure hospitalisations in those at high risk. These agents have now transcended their original glucose‐lowering indication and provide a range of clinical
Daniel Vincent O'Hara, Meg J. Jardine
wiley   +1 more source

Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD). [PDF]

open access: yesElife
Deganutti G   +7 more
europepmc   +1 more source

Volume kinetics of lactated Ringer's solution in adult horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Fluid therapy in horses is primarily empirical. Evidence‐based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objectives To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated ...
William W. Muir   +3 more
wiley   +1 more source

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