Results 111 to 120 of about 53,933 (291)

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone, Erik Moedt, Hiddo J. L. Heerspink, Michael J. Davies, Manon Girard, David Z. I. Cherney, Marcel H. A. Muskiet   +6 more
wiley   +1 more source

Prognostic Value of an Early Response to Tolvaptan and Its Clinical Implications in Patients With Cirrhosis and Hepatic Edema: A Nationwide Multicenter Cohort Study

Hepatology Research, EarlyView.
In a nationwide multicenter cohort, an early response to tolvaptan (≥ 1.5‐kg weight loss within 7 days) was independently associated with improved long‐term survival in patients with cirrhosis and hepatic edema. Early initiation before renal impairment or hyponatremia may optimize treatment response and prognosis. ABSTRACT Aim Hepatic edema indicates a
Kaori Koyano, Taeang Arai, Hidenori Toyoda, Keizo Kato, Joji Tani, Suguru Ogura, Tomomi Okubo, Korenobu Hayama, Norio Itokawa, Toshifumi Tada, Akito Nozaki, Atsushi Hiraoka, Kentaro Matsuura, Toru Ishikawa, Naoto Kawabe, Tsunamasa Watanabe, Koichi Takaguchi, Asahiro Morishita, Hironao Okubo, Motoh Iwasa, Hiroki Nishikawa, Yasuhito Tanaka, Masanori Atsukawa   +22 more
wiley   +1 more source

The diversity of abnormal hormone receptors in adrenal Cushing's syndrome allows novel pharmacological therapies

Brazilian Journal of Medical and Biological Research, 2000
Recent studies from several groups have indicated that abnormal or ectopic expression and function of adrenal receptors for various hormones may regulate cortisol production in ACTH-independent hypercortisolism.
Lacroix A., N'Diaye N., Mircescu H., Tremblay J., Hamet P.   +4 more
doaj  

Vasopressin and oxytocin excite BNST neurons via oxytocin receptors, which reduce anxious arousal

Cell Reports
Summary: Interoceptive signals dynamically interact with the environment to shape appropriate defensive behaviors. Hypothalamic hormones arginine-vasopressin (AVP) and oxytocin (OT) regulate physiological states, including water and electrolyte balance ...
Walter Francesconi, Valentina Olivera-Pasilio, Fulvia Berton, Susan L. Olson, Rachel Chudoba, Lorena M. Monroy, Quirin Krabichler, Valery Grinevich, Joanna Dabrowska   +8 more
doaj   +1 more source

Effects of CSF hormones and ionic composition on salt/water metabolism [PDF]

This collaborative agreement between Drs. Severs and Keil began in 1981, arising from a continuing interest in the issue of what, exactly, are the consequences of headward fluid shifts during manned spaceflight.
Keil, Lanny C., Severs, Walter B.
core   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

Multiple Periapical Lesions Influence the Expression of TLR4/NF‐κB Pathway Components and the Development of Hepatic Injuries in Healthy and Chronic Alcohol‐Consuming Rats

International Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate the impact of multiple apical periodontitis (AP) on the expression of TLR4/NF‐κB pathway components, proinflammatory cytokine levels, and development of hepatic injuries in rats with and without chronic alcohol consumption. Methodology Thirty‐two rats were assigned to four groups (n = 8): Control, AP, Alcohol, and Alcohol+AP ...
Karem Paula Pinto, Isabelle da Cunha Degani, Jenif Braga de Souza, Renata Heisler Neves, Luciana Brandão‐Bezerra, Luciana Moura Sassone, Emmanuel João Nogueira Leal da Silva   +6 more
wiley   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

Journal of Fish Diseases, EarlyView.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami, Elena Bozzetta, Marino Prearo, Paolo Pastorino   +12 more
wiley   +1 more source

GeARF5/GeIAA33‐GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata

Journal of Integrative Plant Biology, EarlyView.
Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu, Zhiqing Wu, Yugang Gao, Yue Xu, Pu Zang, Xinyu Yang, Yan Zhao, Pan Liao, Benoît Boachon, Guoyin Kai   +9 more
wiley   +1 more source

Hypoadrenocorticism‐like syndrome in a cat with Tritrichomonas foetus infection: a case report

Journal of Small Animal Practice, EarlyView.
A reduced sodium: potassium ratio is an uncommon finding in cats, and is typically associated with conditions such as hypoadrenocorticism, severe renal and cardiovascular diseases, cavitary effusion and certain non‐parasitic gastrointestinal diseases.
M. Crisonà, F. Fracassi, A. M. Tardo, S. Okonji, F. Del Baldo   +4 more
wiley   +1 more source