Results 11 to 20 of about 23,143 (229)
Vasopressin receptor antagonists [PDF]
Kidney International, 2006 The first non-peptide vasopressin receptor antagonist (VRA) was recently approved by the United States Food and Drug Administration, and several others are now in late stages of clinical development. Phase 3 trials indicate that these agents predictably reduce urine osmolality, increase electrolyte-free water excretion, and raise serum sodium ...
Arthur Greenberg, Joseph G. Verbalis
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Phosphorylation of the V2 Vasopressin Receptor [PDF]
Journal of Biological Chemistry, 1997 The V2 vasopressin receptor undergoes ligand-induced sequestration and desensitization (Birnbaumer, M., Antaramian, A., Themmen, A. P. N., and Gilbert, S. (1992) J. Biol. Chem. 267, 11783-11788). The V2 receptor expressed in transfected cells labeled with [32P] orthophosphate was phosphorylated following the addition of 100 nM arginine vasopressin (AVP)
INNAMORATI, Giulio +3 more
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Vasopressin and Vasopressin Receptor Antagonists [PDF]
Electrolyte & Blood Pressure, 2008 Vasopressin, a neurohypophyseal peptide hormone, is the endogenous agonist at V1a, V1b, and V2 receptors. The most important physiological function of vasopressin is the maintenance of water homeostasis through interaction with V2 receptors in the kidney.
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Vasopressin V2 receptor antagonists [PDF]
Cardiovascular Research, 2001 Hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and disorders of water retention such as congestive heart failure and cirrhosis is a common problem encountered in the care of the medical patient. Thus far, available treatment modalities for disorders of excess arginine vasopressin (AVP) secretion or action have ...
Joseph G. Verbalis, Lisa L. Wong
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Vasopressin as Possible Treatment Option in Autism Spectrum Disorder
Biomedicines, 2023 Autism spectrum disorder (ASD) is rather common, presenting with prevalent early problems in social communication and accompanied by repetitive behavior.
Kristóf László +6 more
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Aquaretics Use in Acute Decompensated Heart Failure (ADHF) Patients: A Literature Review
Acta Medica Indonesiana, 2022 This is a literature review of the use of aquaretic in patients with acute decompensated heart failure (ADHF), including the physiologic function of vasopressin and its mechanism of action in heart failure patients, and aquaretic drugs with their ...
Norman Sukmadi, Kevin Surya, Arif Sejati
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Arquivos Brasileiros de Cardiologia, 2003 OBJECTIVE: To determine whether arginine vasopressin releases endothelium-derived nitric oxide (EDNO) from the epicardial coronary artery. METHODS: We studied segments of canine left circumflex coronary arteries suspended in organ chambers to measure ...
Paulo Roberto B. Evora +4 more
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Effects of arginine vasopressin on migration and respiratory burst activity in human leukocytes
Open Medicine, 2018 Arginine vasopressin can bind to high-affinity vasopressin V1a receptors in human leukocytes. This study aims to investigate the effects of arginine vasopressin on migration and chemotaxis of neutrophils and oxygen free radical release by human ...
Wiedermann Franz J. +5 more
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Oxytocin modulates human chemosensory decoding of sex in a dose-dependent manner
eLife, 2021 There has been accumulating evidence of human social chemo-signaling, but the underlying mechanisms remain poorly understood. Considering the evolutionarily conserved roles of oxytocin and vasopressin in reproductive and social behaviors, we examined ...
Kepu Chen +3 more
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Vasopressin Receptor Expression in the Placenta [PDF]
Biology of Reproduction, 2003 The arginine vasopressin (AVP) type 1a receptor (V1a) is well known to mediate vasoconstriction. In pregnancy, blood flow in the placenta is crucial for sustaining normal growth and development of the fetus. This is the first AVP receptor study in the placenta and fetal membranes. The aim was to compare, quantitatively, the level of V1a gene expression
Irene Koukoulas +7 more
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