Results 31 to 40 of about 23,143 (229)
Advanced Functional Materials, EarlyView.This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao +9 more
wiley +1 more source
Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2
Nature Communications, 2021 The interaction between a GPCR, such as the vasopressin receptor-2 (V2R), and arrestin depends on the receptors’ phosphorylation pattern. Here authors use FRET and NMR to analyze the phosphorylation patterns of the V2R-arrestin complex and show that ...
Qing-Tao He +15 more
doaj +1 more source
Frontiers in Medicine, 2022 Vasodilatory shock, such as septic shock, requires personalized management which include adequate fluid therapy and vasopressor treatments. While these potent drugs are numerous, they all aim to counterbalance the vasodilatory effects of a systemic ...
Mathieu Jozwiak +7 more
doaj +1 more source
Advanced Synthesis &Catalysis, EarlyView.The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
Advanced Science, EarlyView.This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu +9 more
wiley +1 more source
Transient Phosphorylation of the V1a Vasopressin Receptor [PDF]
Journal of Biological Chemistry, 1998 The V1a arginine vasopressin receptor (V1aR) expressed in HEK 293 cells was phosphorylated after binding to arginine vasopressin (AVP). The phosphate was incorporated very rapidly into the protein but remained attached for a very short time despite the continuous presence of hormone.
INNAMORATI, Giulio +2 more
openaire +4 more sources
Jornal de Pediatria, 2007 OBJETIVO: A vasopressina é um hormônio neuropeptídico utilizado clinicamente há mais de 50 anos, com papel importante na homeostase circulatória e na regulação da osmolalidade sérica.
Elisa Baldasso +3 more
doaj +1 more source
Advanced Science, EarlyView.This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu +17 more
wiley +1 more source
Vasopressin receptors V1aand V2 are not osmosensors [PDF]
Physiological Reports, 2015 Herein, we investigated whether G protein-coupled signaling via the vasopressin receptors of the V1a and V2 subtypes (V1aR and V2R) could be obtained as a direct response to hyperosmolar challenges and/or whether hyperosmolar challenges could augment classical vasopressin-dependent V1aR signaling.
Pedersen, Kasper Lykke +4 more
openaire +4 more sources
Frontiers in EndocrinologyVasopressin and oxytocin are well known and evolutionarily ancient modulators of social behavior. The distribution and relative densities of vasopressin and oxytocin receptors are known to modulate the sensitivity to these signaling molecules ...
Angela R. Freeman +7 more
doaj +1 more source