Results 51 to 60 of about 580,482 (298)

Physiopathology of hereditary polyuric states: a molecular view of renal function

Swiss Medical Weekly, 2012
Recent discoveries have shed new light on the understanding of water metabolism: (1.) in addition to hypothalamic osmoreceptor cells expressing a TRPV1 variant, there are peripheral TRPV4 receptors sensing tonicity in the portal vein and changing ...
Daniel G. Bichet
doaj   +1 more source

Clinical Efficiency of Vasopressin or Its Analogs in Comparison With Catecholamines Alone on Patients With Septic Shock: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2020
BackgroundVasopressin is an efficient remedy for septic shock patients as its great capacity in promoting hemodynamic stabilization. The aim of current systematic review and meta-analysis is to compare the clinical efficiency of vasopressin or its ...
Ren-qi Yao, Ren-qi Yao, De-meng Xia, Li-xue Wang, Guo-sheng Wu, Yi-bing Zhu, Hong-qiang Zhao, Qi Liu, Zhao-fan Xia, Chao Ren, Yong-ming Yao   +10 more
doaj   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Gene regulation of vasopressin and vasopressin receptors in cancer

Experimental Physiology, 2000
It is proposed that neuropeptide production by tumours is an important part of a special process of oncogenic transformation rather than a pre‐existing condition of progenitor cells; this concept is called Selective Tumour gene Expression of Peptides essential for Survival (STEPS).
openaire   +2 more sources

Cation Diffusion‐Mediated Displaced Reaction‐Transformation in Green Steelmaking

Advanced Science, EarlyView.
The removal of O lattice atoms by environmental H2 at the surface of Fe3O4 results in Fe enrichment, driving the inward diffusion of Fe cations into the bulk. Through hopping between unoccupied and initially occupied sites, cation diffusion triggers a spatially displaced reaction‐transformation and drives subsequent dynamic phase transformations and ...
Guangyi Guo, Paul Paciok, Baptiste Bienvenu, Longqi Bai, Barak Ratzker, Marc Heggen, Xuyang Zhou, Dierk Raabe   +7 more
wiley   +1 more source

Metabolic effects of vasopressin in pathophysiology of diabetic kidney disease

Frontiers in Endocrinology, 2023
The diabetic kidney disease (DKD) is the major cause of the chronic kidney disease (CKD). Enhanced plasma vasopressin (VP) levels have been associated with the pathophysiology of DKD and CKD.
Svetlana Lebedeva, Arus Margaryan, Elena Smolyarchuk, Andrey Nedorubov, Maria Materenchuk, Alexander Tonevitsky, Kerim Mutig, Kerim Mutig   +7 more
doaj   +1 more source

Transient Phosphorylation of the V1a Vasopressin Receptor [PDF]

Journal of Biological Chemistry, 1998
The V1a arginine vasopressin receptor (V1aR) expressed in HEK 293 cells was phosphorylated after binding to arginine vasopressin (AVP). The phosphate was incorporated very rapidly into the protein but remained attached for a very short time despite the continuous presence of hormone.
INNAMORATI, Giulio, H. Sadeghi, M. Birnbaumer   +2 more
openaire   +3 more sources

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Characterization of oxytocin and vasopressin receptors in the Southern giant pouched rat and comparison to other rodents

Frontiers in Endocrinology
Vasopressin and oxytocin are well known and evolutionarily ancient modulators of social behavior. The distribution and relative densities of vasopressin and oxytocin receptors are known to modulate the sensitivity to these signaling molecules ...
Angela R. Freeman, Angela R. Freeman, Samanta Arenas, Danielle N. Lee, Danielle N. Lee, Bhupinder Singh, Bhupinder Singh, Alexander G. Ophir   +7 more
doaj   +1 more source

Therapeutic Potential of Vasopressin-Receptor Antagonists in Heart Failure

Journal of Pharmacological Sciences, 2014
.: Arginine vasopressin (AVP) is a 9-amino acid peptide that is secreted from the posterior pituitary in response to high plasma osmolality and hypotension.
Yasukatsu Izumi, Katsuyuki Miura, Hiroshi Iwao   +2 more
doaj   +1 more source