Results 211 to 220 of about 4,142,916 (290)

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Cell binding, uptake, and infection of influenza A virus using recombinant antibody-based receptors. [PDF]

J Virol
Adu OF, Sempere Borau M, Früh SP, Karakus U, Weichert WS, Wasik BR, Stertz S, Parrish CR.   +7 more
europepmc   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Antiviral nanomedicine: Advantages, mechanisms and advanced therapies. [PDF]

Bioact Mater
Pu Y, Zhu C, Liao J, Gong L, Wu Y, Liu S, Wang H, Zhang Q, Lin Z.   +8 more
europepmc   +1 more source

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

Advanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim, Hyeongseop Keum, Hassan Albadawi, Ismail Altinbasak, Furkan Yavuz, Erin H. Graf, Nitin Mishra, Rahmi Oklu   +7 more
wiley   +1 more source

Soluble SARS-CoV-2 Spike glycoprotein: considering some potential pathogenic effects. [PDF]

Front Immunol
Azzarone B, Landolina N, Mariotti FR, Moretta L, Maggi E.   +4 more
europepmc   +1 more source

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

Genetic diversity of A(H5N1) avian influenza viruses isolated from birds and seals in Russia in 2023. [PDF]

Sci Rep
Panova AS, Kolosova NP, Svyatchenko SV, Goncharova NI, Danilenko AV, Boldyrev ND, Shadrinova KN, Vasiltsova NN, Egorova ML, Onkhonova GS, Gudymo AS, Bragina MK, Ryzhikov AB, Marchenko VY.   +13 more
europepmc   +1 more source

The Two Groups of Zebrafish Virus-Induced Interferons Signal via Distinct Receptors with Specific and Shared Chains1

Journal of Immunology, 2009
Dina Aggad, M. Mazel, P. Boudinot, K. Mogensen, O. J. Hamming, R. Hartmann, S. Kotenko, P. Herbomel, G. Lutfalla, J. Levraud   +9 more
semanticscholar   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source