Results 71 to 80 of about 235,128 (161)

Sialic Acid Receptor Specificity in Mammary Gland of Dairy Cattle Infected with Highly Pathogenic Avian Influenza A(H5N1) Virus

Emerging Infectious Diseases
In March 2024, the US Department of Agriculture’s Animal and Plant Health Inspection Service reported detection of highly pathogenic avian influenza (HPAI) A(H5N1) virus in dairy cattle in the United States for the first time. One factor that determines
Rahul K. Nelli, Tyler A. Harm, Chris Siepker, Jennifer M. Groeltz-Thrush, Brianna Jones, Ning-Chieh Twu, Ariel S. Nenninger, Drew R. Magstadt, Eric R. Burrough, Pablo E. Piñeyro, Marta Mainenti, Silvia Carnaccini, Paul J. Plummer, Todd M. Bell   +13 more
doaj   +1 more source

The Natural Selection of Herpesviruses and Virus-Specific NK Cell Receptors

Viruses, 2009
During the co-evolution of cytomegalovirus (CMV) and natural killer (NK) cells, each has evolved specific tactics in an attempt to prevail. CMV has evolved multiple immune evasion mechanisms to avoid detection by NK cells and other immune cells, leading ...
Joseph C. Sun, Lewis L. Lanier
doaj   +1 more source

Viral modulation of interferon (IFN) responses to african swine fever virus (ASFV) [PDF]

, 2011
Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A imunidade inata constitui a primeira resposta dada por um hospedeiro quando atacado por agentes patogénicos. A resposta imune baseia-se em genes
Costa, Emanuel Nery de Oliveira Quartin, 1986-
core  

IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

eLife, 2018
Host factors restricting the transmission of respiratory viruses are poorly characterized. We analyzed the contribution of type I and type III interferon (IFN) using a mouse model in which the virus is selectively administered to the upper airways ...
Jonas Klinkhammer, Daniel Schnepf, Liang Ye, Marilena Schwaderlapp, Hans Henrik Gad, Rune Hartmann, Dominique Garcin, Tanel Mahlakõiv, Peter Staeheli   +8 more
doaj   +1 more source

Glyco-engineered MDCK cells display preferred receptors of H3N2 influenza absent in eggs used for vaccines

Nature Communications, 2023
Evolution of human H3N2 influenza viruses driven by immune selection has narrowed the receptor specificity of the hemagglutinin (HA) to a restricted subset of human-type (Neu5Acα2-6 Gal) glycan receptors that have extended poly-LacNAc (Galβ1-4GlcNAc ...
Chika Kikuchi, Aristotelis Antonopoulos, Shengyang Wang, Tadashi Maemura, Rositsa Karamanska, Chiara Lee, Andrew J. Thompson, Anne Dell, Yoshihiro Kawaoka, Stuart M. Haslam, James C. Paulson   +10 more
doaj   +1 more source

Syrian hamster is a valuable animal model for evaluating the transmissibility of emerging influenza viruses

Emerging Microbes and Infections
Multiple influenza virus subtypes actively circulate in nature, and assessing their transmissibility provides crucial information for predicting their pandemic potential and for pandemic preparedness.
Jiongjie Li, Dongxue Wang, Bin Li, Jinming Ma, Xinwen He, Lei Chen, Huihui Kong, Guohua Deng, Pengfei Cui, Huanliang Yang, Fei Meng, Xianying Zeng, Guobin Tian, Jianzhong Shi, Hualan Chen   +14 more
doaj   +1 more source

Host factors and early treatments to restrict paediatric HIV infection and early disease progression [PDF]

, 2015
open6noA body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions.
De Rossi, Anita, Freguja, Riccardo, Gianesin, Ketty, Giaquinto, Carlo, Petrara, Raffaella, Zanchetta, Marisa   +5 more
core   +1 more source

Identifying the immune interactions underlying HLA class I disease associations

eLife, 2020
Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci.
Bisrat J Debebe, Lies Boelen, James C Lee, IAVI Protocol C Investigators, Chloe L Thio, Jacquie Astemborski, Gregory Kirk, Salim I Khakoo, Sharyne M Donfield, James J Goedert, Becca Asquith   +10 more
doaj   +1 more source

m6a RNA methylation: the implications for health and disease [PDF]

, 2014
The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core   +1 more source

Influenza Infection in Wild Raccoons

Emerging Infectious Diseases, 2008
Raccoons (Procyon lotor) are common, widely distributed animals that frequently come into contact with wild waterfowl, agricultural operations, and humans. Serosurveys showed that raccoons are exposed to avian influenza virus.
Jeffrey S. Hall, Kevin T. Bentler, Gabrielle Landolt, Stacey A. Elmore, Richard B. Minnis, Tyler A. Campbell, Scott C. Barras, J. Jeffrey Root, John Pilon, Kristy Pabilonia, Cindy Driscoll, Dennis Slate, Heather Sullivan, Robert G. McLean   +13 more
doaj   +1 more source