Results 221 to 230 of about 5,994,707 (387)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Promiscuity and specificity in ligand sensing by plant cell surface receptors. [PDF]

PLoS Pathog
Steidele CE, Gronnier J, Stegmann M, Hückelhoven R, Ried-Lasi MK.   +4 more
europepmc   +1 more source

Distribution of Cell Receptors and Simple Sugar Inhibitors During Encephalomyocarditis Virus-Cell Union [PDF]

, 1967
Calvin M. Kunin
openalex   +1 more source

The RXR heterodimers and orphan receptors

Cell, 1995
D. Mangelsdorf, R. Evans
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Identification of a G Protein-Coupled Receptor for Buccalin-Type Peptides in the Mollusk <i>Aplysia</i>: Evolutionary Insights into Neuropeptide Signaling. [PDF]

ACS Omega
Xu JP, Ding XY, Jin QC, Zhang YL, Chang JH, Jiang HM, Li YD, Fu P, Zhang YC, Liu CP, Mao RT, Liu CY, Li F, Wu SQ, Cropper EC, Zhang G, Jing J.   +16 more
europepmc   +1 more source

Evidence for a central 5‐hydroxytryptamine receptor stimulation by lysergic acid diethylamide [PDF]

, 1968
N.‐E. Andén, H. Corrodi, Kjell Fuxé, Tomas Hökfelt   +3 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Expression of Genes Encoding Receptors for Classical Neurotransmitters, Neuropeptides and Hormones in the Substantia Nigra, Especially in Dopaminergic Neurons, in Intact Mice and Mouse Models of Parkinson's Disease. [PDF]

Cells
Troshev D, Pavlova E, Bogdanov V, Ugrumov M.   +3 more
europepmc   +1 more source

The Properties of the Receptors in the Axon Reflex Sweating Produced by Nicotine and Sodium Chloride

, 1954
Masao Wada
openalex   +1 more source