Results 21 to 30 of about 89,607 (287)

Ebola outbreak in Guinea, 2021: Clinical care of patients with Ebola virus disease

Southern African Journal of Infectious Diseases, 2023
Background: Experience from the Zaire Ebolavirus epidemic in the eastern Democratic Republic of the Congo (2018–2020) demonstrates that early initiation of essential critical care and administration of Zaire Ebolavirus specific monoclonal antibodies may ...
Boyo C. Pare, Alseny M. Camara, Aminata Camara, Moussa Kourouma, Koivogui Enogo, Mohammed S. Camara, Laurent Akilimali, Sayadi Sani, Eric Barte de Sainte Fare, Papys Lame, Nicolas Mouly, Marta Lado Castro-Rial, Billy Sivahera, Mahamoud S. Cherif, Abdoul H. Beavogui, Dally Muamba, Joachim B. Tamba, Barry Moumié, Richard Kojan, Hans-Joerg Lang   +19 more
doaj   +1 more source

Evaluating artesunate monotherapy and dihydroartemisinin-piperaquine as potential antimalarial options for prevaccination radical cures during future malaria vaccine field efficacy trials

Malaria Journal
Background In malaria vaccine clinical trials, immune responses after vaccination may be compromised due to immunosuppression caused by concurrent Plasmodium falciparum infection.
Alphonse Ouédraogo, Daouda Ouattara, San Maurice Ouattara, Amidou Diarra, Emilie S. Badoum, Alimatou Hema, Amidou Z. Ouédraogo, Denise Hien, Edith C. Bougouma, Issa Nébié, Valéry Bocquet, Michel Vaillant, Alfred B. Tiono, Sodiomon B. Sirima   +13 more
doaj   +1 more source

Mettre en œuvre l’action publique pour réduire l’usage des pesticides : reconnaître les activités d’intermédiation

Cahiers Agricultures, 2021
Malgré de nombreuses mesures d’accompagnement à la réduction des pesticides, leur usage ne cesse de croître en France. Doit-on pour autant considérer que rien ne change ?
Cardona Aurélie, Cerf Marianne, Barbier Marc   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Incidence and antimicrobial resistance of non-typhoidal Salmonella enterica in stool samples from children under five in peri-urban Ouagadougou, Burkina Faso

BMC Microbiology
Background Non-typhoidal Salmonella (NTS) causes significant illness worldwide, particularly in sub-Saharan Africa. Poor sanitation, limited healthcare, and rising antimicrobial resistance (AMR) worsen its impact on children under five.
Alimatou Héma, Ben I. Soulama, Jean Sawadogo, Amidou Z. Ouédraogo, Denise Hien, Issa Nébié, Sophie Houard, Alphonse Ouédraogo, Alfred B. Tiono, Mahamoudou Sanou, Sodiomon B. Sirima   +10 more
doaj   +1 more source

Force of Infection (FOI) and Multiplicity of Infection (MOI) in Plasmodium falciparum Infected Children Aged 1.5–12 Years Living in the Malaria Endemic Area of Banfora, Burkina Faso

Pathogens
The aim of this study was to explore molecular measures of P. falciparum malaria burden (FOI and MOI) in the context of seasonal malaria chemoprevention. We analyzed malaria cases collected as part of a longitudinal cohort study.
Emilie S. Badoum, Ludovic Kouraogo, Amidou Diarra, Daouda Ouattara, Issa Nebie, Alphonse Ouedraogo, Alfred B. Tiono, Sodiomon B. Sirima   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Multiple first-line therapeutic strategies to mitigate artemisinin resistance: cost analysis of a pilot study from a health system perspective in Kaya health district, Burkina Faso

Malaria Journal
Background The emergence of artemisinin resistance in Africa is an increasingly evident threat to malaria control and elimination, and anticipatory measures are needed.
Rosemonde M. Guissou, Jean Moïse T. Kaboré, Issiaka Soulama, Denise Hien, Yacouba Nombré, Alfred B. Tiono, Christian Burri, Sodiomon B. Sirima   +7 more
doaj   +1 more source

Ensemble Sauvons la forêt de Chantilly. Une recherche action collective de territoire face à un dépérissement forestier massif

Revue Forestière Française, 2023
Depuis vingt ans, un dépérissement massif affecte la chênaie de Chantilly, lié à un environnement pédologique limite pour le Chêne pédonculé, essence majoritaire : des sols sableux reposant sur des plateaux calcaires.
Hervé Le Bouler
doaj   +1 more source