Results 51 to 60 of about 10,855,625 (286)

Considérations comparatives sur les recherches géométriques modernes [PDF]

Annales scientifiques de l'École normale supérieure, 1891
© Gauthier-Villars (Editions scientifiques et medicales Elsevier), 1891, tous droits reserves. L’acces aux archives de la revue « Annales scientifiques de l’E.N.S. » (http://www. elsevier.com/locate/ansens), implique l’accord avec les conditions generales d’utilisation (http://www.numdam.org/legal.php).
openaire   +1 more source

Données anonymes concernant les candidatures au premier prix science ouverte du logiciel libre de la recherche

, 2023
Quelques informations anonymes concernant les 129 candidatures au premier prix science ouverte du logiciel libre de ...
Le Berre, Daniel
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Recherche sociale

, 1999
TrimestrielFait suite à: Recherche ...
Conseil québécois de la recherche sociale
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Association between genetic clades and cancer prevalence suggested by French-wide study of oncogenic small ruminant β-retrovirus diversity

Frontiers in Cellular and Infection Microbiology
IntroductionENTV (Enzootic Nasal Tumor Virus) and JSRV (Jaagsiekte Sheep Retrovirus) are β-retroviruses responsible for respiratory cancers in sheep and goats.
Benjamin Riocreux-Verney, Marie Verneret, Marie Verneret, Rémi Diesler, Christine Dolmazon, Barbara Gineys, Jean-Luc Cadoré, Jean-Luc Cadoré, Jocelyn Turpin, Caroline Leroux   +9 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Recherche et formation

, 1994
Publ. comme le no 15 - 1994 de la revue Recherche et formationBibliogr.
Institut national de recherche pédagogique (France)
core   +1 more source

The Antisense Protein ASP of HIV-1 Enhances Viral Entry in CD4+ T Cells

Viruses
The negative strand of the human immunodeficiency virus-1 (HIV-1) proviral genome contains an antisense open reading frame encoding a protein (ASP) with no known homologs.
Myriam Abla Houmey, Isabella Caico, Aurélie Rivault, Lucile Espert, Jean-Michel Mesnard, Fabio Romerio, Nathalie Chazal   +6 more
doaj   +1 more source